Results 31 to 40 of about 16,991 (224)

Degrees of freedom effect on fragmentation in tandem mass spectrometry of singly charged supramolecular aggregates of sodium sulfonates [PDF]

, 2013
The characteristic collision energy (CCE) to obtain 50% fragmentation of positively and negatively single charged non-covalent clusters has been measured.
TURCO LIVERI, Vincenzo, Indelicato, S, Drahos, László, Liveri, Vincenzo Turco, Drahos, L, TuriàK, L, Indelicato, Serena, Vèkey, K, Vékey, Károly, Turiák, Lilla, Bongiorno, David, Indelicato, Sergio, Ceraulo, Leopoldo   +12 more
core   +1 more source

Nanospray Desorption Electrospray Ionization (nano-DESI) Mass Spectrometry Imaging of Drift Time-Separated Ions

, 2020
Simultaneous spatial localization and structural characterization of molecules in complex biological samples currently represents an analytical challenge for mass spectrometry imaging (MSI) techniques.
ruichuan, yin, Daisy, Unsihuay, Yingju, Li, Xiaofei, Sun, Sudhansu, Dey, Daniela Mesa, Sanchez, Julia, Laskin   +6 more
core   +1 more source

Using mass spectrometry imaging to map fluxes quantitatively in the tumor ecosystem

Nature Communications, 2023
Tumors are comprised of a multitude of cell types spanning different microenvironments. Mass spectrometry imaging (MSI) has the potential to identify metabolic patterns within the tumor ecosystem and surrounding tissues, but conventional workflows have ...
Michaela Schwaiger-Haber, Ethan Stancliffe, Dhanalakshmi S. Anbukumar, Blake Sells, Jia Yi, Kevin Cho, Kayla Adkins-Travis, Milan G. Chheda, Leah P. Shriver, Gary J. Patti   +9 more
doaj   +1 more source

Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI)

Toxicon: X, 2020
Amphibian cutaneous glands secrete toxins used in different vital functions including passive defense. Through Desorption Electrospray Ionization-Imaging we analyzed the distribution of the major toxins of the toad Rhinella marina parotoid macroglands ...
Pedro L. Mailho-Fontana, Andreia M. Porcari, Marcos N. Eberlin, Carlos Jared, Marta Maria Antoniazzi, Daniel C. Pimenta, Juliana M. Sciani   +6 more
doaj   +1 more source

Multicenter Study Using Desorption-Electrospray-Ionization-Mass-Spectrometry Imaging for Breast-Cancer Diagnosis

, 2018
The histological and molecular subtypes of breast cancer demand distinct therapeutic approaches. Invasive ductal carcinoma (IDC) is subtyped according to estrogen-receptor (ER), progesterone-receptor (PR), and HER2 status, among other markers. Desorption-
Luis Otávio Sarian (5759609), Geisilene R. Paiva, Chandandeep Nagi, Luis Otávio Sarian, Livia S. Eberlin, Stacey A. Carter (5759606), Jialing Zhang, Stacey A. Carter, John Q. Lin (5622686), Marcos N. Eberlin (745128), Robert Tibshirani, Raquel M. Rodrigues-Peres, Kyana Y. Garza (5622683), Jonathan H. Young, Chandandeep Nagi (286802), Livia S. Eberlin (461381), Raquel M. Rodrigues-Peres (5759597), Geisilene R. Paiva (5759603), Andreia M. Porcari, Marcos N. Eberlin, Jialing Zhang (1317267), Jonathan H. Young (5759600), Andreia M. Porcari (5759594), Robert Tibshirani (196), Kyana Y. Garza, John Q. Lin   +25 more
core   +1 more source

Single-Cell Analysis and Its Applications by Surface Desorption Ambient Mass Spectrometry

Zhipu Xuebao
As the fundamental units of the structure and function of living organisms, cells perform the core functions of life activities. With the deepening research in life sciences, the importance of studies on cellular heterogeneity has become increasingly ...
Dan LIN, Xi-yang GE, Xin-er XING, Yong HE, Jin OUYANG, Na NA   +5 more
doaj   +1 more source

The foundations and development of lipidomics

Journal of Lipid Research, 2022
For over a century, the importance of lipid metabolism in biology was recognized but difficult to mechanistically understand due to the lack of sensitive and robust technologies for identification and quantification of lipid molecular species.
Xianlin Han, Richard W. Gross
doaj   +1 more source

Evaluation of Quantitative Platforms for Single Target Mass Spectrometry Imaging

Pharmaceuticals, 2022
(1) Imaging of pharmaceutical compounds in tissue is an increasingly important subsection of Mass Spectrometry Imaging (MSI). Identifying proper target engagement requires MS platforms with high sensitivity and spatial resolution.
Andrew P. Bowman, James Sawicki, Nari N. Talaty, Wayne R. Buck, Junhai Yang, David S. Wagner   +5 more
doaj   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Methods for structural characterisation of Quillaja saponins by electrospray ionisation ion trap multiple-stage mass spectrometry [PDF]

, 2008
This thesis describes methods for structural classification of Quillaja saponins based on high performance liquid chromatography hyphenated electrospray ionisation ion trap multiple-stage mass spectrometry, in combination with multivariate analysis ...
Bankefors, Johan
core