Results 21 to 30 of about 322,846 (227)

Modular mass spectrometric tool for analysis of composition and phosphorylation of protein complexes. [PDF]

open access: yesPLoS ONE, 2007
The combination of high accuracy, sensitivity and speed of single and multiple-stage mass spectrometric analyses enables the collection of comprehensive sets of data containing detailed information about complex biological samples.
Justin D Blethrow   +3 more
doaj   +1 more source

Desorption Electrospray Ionization-Mass Spectrometry of Proteins [PDF]

open access: yesAnalytical Chemistry, 2007
Desorption electrospray ionization-mass spectrometry (DESI-MS) was evaluated for the detection of proteins ranging in molecular mass from 12 to 66 kDa. Proteins were uniformly deposited on a solid surface without pretreatment and analyzed with a DESI source coupled to a quadrupole ion trap mass spectrometer.
Yong-Seung, Shin   +4 more
openaire   +2 more sources

Research Progress of Highly Selective Solid Substrate Electrospray Ionization Sources for Mass Spectrometry [PDF]

open access: yesZhipu Xuebao, 2022
Solid substrate electrospray mass spectrometry is an ambient mass spectrometry method that involves carrying, ionization and detection of the samples. This approach has a wide range of applications, and which is appropriate for rapid mass spectrometric ...
ZHANG Feng;MU Guo-dong;LIU Tong
doaj  

Enhancing Metabolomic Coverage in Positive Ionization Mode Using Dicationic Reagents by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

open access: yesMetabolites, 2021
Mass spectrometry imaging is a powerful tool to analyze a large number of metabolites with their spatial coordinates collected throughout the sample. However, the significant differences in ionization efficiency pose a big challenge to metabolomic mass ...
Ying Xi, David C. Muddiman
doaj   +1 more source

Desorption Electrospray Ionization (DESI) Mass Spectrometric Imaging of the Distribution of Rohitukine in the Seedling of Dysoxylum binectariferum Hook. F. [PDF]

open access: yesPLoS ONE, 2016
Ambient ionization mass spectrometric imaging of all parts of the seedling of Dysoxylum binectariferum Hook. f (Meliaceae) was performed to reconstruct the molecular distribution of rohitukine (Rh) and related compounds.
Patel Mohana Kumara   +5 more
doaj   +1 more source

Spatially-resolved in vivo plant metabolomics by laser ablation-based mass spectrometry imaging (MSI) techniques: LDI-MSI and LAESI

open access: yesFrontiers in Plant Science, 2015
This short review aims to summarize the current developments and applications of mass spectrometry-based methods for in situ profiling and imaging of plants with minimal or no sample pre-treatment or manipulation.
Aleš eSvatoš, Benjamin eBartels
doaj   +1 more source

Hardware and software solutions for implementing nanospray desorption electrospray ionization (nano-DESI) sources on commercial mass spectrometers. [PDF]

open access: yesJ Mass Spectrom
Nanospray desorption electrospray ionization (nano-DESI) is an ambient ionization mass spectrometry imaging (MSI) approach that has been used for imaging of biological and environmental samples with high spatial resolution and throughput.
Jiang LX, Hilger RT, Laskin J.
europepmc   +3 more sources

Single Cell Metabolomics: A Future Tool to Unmask Cellular Heterogeneity and Virus-Host Interaction in Context of Emerging Viral Diseases

open access: yesFrontiers in Microbiology, 2020
Viral emergence is an unpredictable but obvious event, particularly in the era of climate change and globalization. Efficient management of viral outbreaks depends on pre-existing knowledge and alertness.
Rajesh Kumar   +3 more
doaj   +1 more source

Nanospray Desorption Electrospray Ionization (nano-DESI) Mass Spectrometry Imaging of Drift Time-Separated Ions [PDF]

open access: yes, 2020
Simultaneous spatial localization and structural characterization of molecules in complex biological samples currently represents an analytical challenge for mass spectrometry imaging (MSI) techniques.
ruichuan, yin   +6 more
core   +1 more source

Direct Ambient Analysis of Pharmaceutical and Ecstasy Tablets

open access: yesCHIMIA, 2006
Desorption electrospray ionization (DESI) is a new ionization technique recently introduced in analytical chemistry for the ambient analysis of surfaces by mass spectrometry.
Luc Alexis Leuthold   +6 more
doaj   +1 more source

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