Results 21 to 30 of about 38,846 (279)

Enhanced desorption ionization using oxidizing electrosprays [PDF]

Journal of the American Society for Mass Spectrometry, 2006
A signal enhancement of two orders of magnitude was achieved when reactive desorption electrospray ionization (DESI) was used to investigate copper(II) dibutyl dithiocarbamate, Cu(II)(bu2dtc)2, found in a specialized polymer. Cu(II) was oxidized to Cu(III) during the DESI experiment by oxidants in the spray solvent.
Nefliu, Marcela, Cooks, R. Graham, Moore, Colin   +2 more
openaire   +2 more sources

Analytical Performance Evaluation of New DESI Enhancements for Targeted Drug Quantification in Tissue Sections

Pharmaceuticals, 2022
Desorption/ionization (DI)-mass spectrometric (MS) methods offer considerable advantages of rapidity and low-sample input for the analysis of solid biological matrices such as tissue sections.
Margaux Fresnais, Siwen Liang, Marius Breitkopf, Joshua Raoul Lindner, Emmanuelle Claude, Steven Pringle, Pavel A. Levkin, Konstantin Demir, Julia Benzel, Julia Sundheimer, Britta Statz, Kristian W. Pajtler, Stefan M. Pfister, Walter E. Haefeli, Jürgen Burhenne, Rémi Longuespée   +15 more
doaj   +1 more source

Desorption Electrospray Ionization-Mass Spectrometry of Proteins [PDF]

Analytical Chemistry, 2007
Desorption electrospray ionization-mass spectrometry (DESI-MS) was evaluated for the detection of proteins ranging in molecular mass from 12 to 66 kDa. Proteins were uniformly deposited on a solid surface without pretreatment and analyzed with a DESI source coupled to a quadrupole ion trap mass spectrometer.
Yong-Seung, Shin, Barbara, Drolet, Richard, Mayer, Kurt, Dolence, Franco, Basile   +4 more
openaire   +2 more sources

Modular mass spectrometric tool for analysis of composition and phosphorylation of protein complexes. [PDF]

PLoS ONE, 2007
The combination of high accuracy, sensitivity and speed of single and multiple-stage mass spectrometric analyses enables the collection of comprehensive sets of data containing detailed information about complex biological samples.
Justin D Blethrow, Chao Tang, Changhui Deng, Andrew N Krutchinsky   +3 more
doaj   +1 more source

Research Progress of Highly Selective Solid Substrate Electrospray Ionization Sources for Mass Spectrometry [PDF]

Zhipu Xuebao, 2022
Solid substrate electrospray mass spectrometry is an ambient mass spectrometry method that involves carrying, ionization and detection of the samples. This approach has a wide range of applications, and which is appropriate for rapid mass spectrometric ...
ZHANG Feng;MU Guo-dong;LIU Tong
doaj  

Enhancing Metabolomic Coverage in Positive Ionization Mode Using Dicationic Reagents by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

Metabolites, 2021
Mass spectrometry imaging is a powerful tool to analyze a large number of metabolites with their spatial coordinates collected throughout the sample. However, the significant differences in ionization efficiency pose a big challenge to metabolomic mass ...
Ying Xi, David C. Muddiman
doaj   +1 more source

High-throughput label-free opioid receptor binding assays using an automated desorption electrospray ionization mass spectrometry platform.

Chem Commun (Camb)
Feng Y, Morato NM, Huang KH, Lin M, Cooks RG.   +4 more
europepmc   +3 more sources

Recent advances in experimental techniques to probe fast excited-state dynamics in biological molecules in the gas phase : dynamics in nucleotides, amino acids and beyond [PDF]

, 2013
In many chemical reactions, an activation barrier must be overcome before a chemical transformation can occur. As such, understanding the behaviour of molecules in energetically excited states is critical to understanding the chemical changes that these ...
Hadden DJ, Lodish H, Rossle S, Satzger H, Scoles G, Vastola FJ, Yang X   +6 more
core   +1 more source

Advancing liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry toward ultra-high-throughput analysis [PDF]

, 2020
Label-free high-throughput screening using mass spectrometry has the potential to provide rapid large-scale sample analysis at a speed of more than one sample per second.
Brown, Jeffery, Cramer, Rainer, Hartmane, Evita, Krenkel, Henriette, Morris, Michael, Piras, Cristian   +5 more
core   +1 more source

Spatially-resolved in vivo plant metabolomics by laser ablation-based mass spectrometry imaging (MSI) techniques: LDI-MSI and LAESI

Frontiers in Plant Science, 2015
This short review aims to summarize the current developments and applications of mass spectrometry-based methods for in situ profiling and imaging of plants with minimal or no sample pre-treatment or manipulation.
Aleš eSvatoš, Benjamin eBartels
doaj   +1 more source