Results 21 to 30 of about 376,084 (233)

A:Recent advances in ambient electrospray ionization technologies [PDF]

open access: yesRecords of Pharmaceutical & Biomedical Sciences, 2020
Mass spectrometry is one of the most powerful techniques for detection and identification. Due to its sensitivity and selectivity, exact mass of analytes, and in effect, their relative fragments, allow for total structure information.
Sara Amer   +6 more
doaj   +1 more source

Nanospray Desorption Electrospray Ionization Mass Spectrometry Imaging (nano-DESI MSI): A Tutorial Review [PDF]

open access: yesACS Measurement Science Au
Mushfeqa Iqfath   +4 more
doaj   +2 more sources

Advances in MALDI Mass Spectrometry Imaging Single Cell and Tissues

open access: yesFrontiers in Chemistry, 2022
Compared with conventional optical microscopy techniques, mass spectrometry imaging (MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique, which can sensitively and simultaneously detect, quantify, and map hundreds of ...
Xiaoping Zhu   +6 more
doaj   +1 more source

Inter-platform assessment of performance of high-throughput desorption electrospray ionization mass spectrometry

open access: yesTalanta Open, 2021
High throughput analysis is increasingly relevant in both industry and academia, with applications reaching from enzymology and drug discovery to organic reaction optimization and diagnostics.
Nicolás M. Morato, R. Graham Cooks
doaj   +1 more source

Analytical Performance Evaluation of New DESI Enhancements for Targeted Drug Quantification in Tissue Sections

open access: yesPharmaceuticals, 2022
Desorption/ionization (DI)-mass spectrometric (MS) methods offer considerable advantages of rapidity and low-sample input for the analysis of solid biological matrices such as tissue sections.
Margaux Fresnais   +15 more
doaj   +1 more source

Enhanced desorption ionization using oxidizing electrosprays [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2006
A signal enhancement of two orders of magnitude was achieved when reactive desorption electrospray ionization (DESI) was used to investigate copper(II) dibutyl dithiocarbamate, Cu(II)(bu2dtc)2, found in a specialized polymer. Cu(II) was oxidized to Cu(III) during the DESI experiment by oxidants in the spray solvent.
Nefliu, Marcela   +2 more
openaire   +2 more sources

Surface Scanning Analysis of Planar Arrays of Analytes with Desorption Electrospray Ionization-Mass Spectrometry

open access: yes, 2016
The analysis of analytes deposited on, separated on, or otherwise distributed about a planar surface using desorption electrospray ionization mass spectrometry in a surface scanning sampling mode was investigated.
Vilmos Kertesz (1364223)   +2 more
core   +4 more sources

Salt tolerance of desorption electrospray ionization (DESI) [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2007
The salt tolerance of desorption electrospray ionization (DESI) was systematically investigated by examining three different drug mixtures in the presence of 0, 0.2, 2, 5, 10, and 20% NaCl:KCl (1:1) from different surfaces. At physiological salt concentrations, the individual drugs in each mixture were observed in each experiment.
Jackson, Ayanna U.   +3 more
openaire   +2 more sources

Modular mass spectrometric tool for analysis of composition and phosphorylation of protein complexes. [PDF]

open access: yesPLoS ONE, 2007
The combination of high accuracy, sensitivity and speed of single and multiple-stage mass spectrometric analyses enables the collection of comprehensive sets of data containing detailed information about complex biological samples.
Justin D Blethrow   +3 more
doaj   +1 more source

Desorption Electrospray Ionization-Mass Spectrometry of Proteins [PDF]

open access: yesAnalytical Chemistry, 2007
Desorption electrospray ionization-mass spectrometry (DESI-MS) was evaluated for the detection of proteins ranging in molecular mass from 12 to 66 kDa. Proteins were uniformly deposited on a solid surface without pretreatment and analyzed with a DESI source coupled to a quadrupole ion trap mass spectrometer.
Yong-Seung, Shin   +4 more
openaire   +2 more sources

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