Results 41 to 50 of about 38,846 (279)

Rapid deconvolution of low-resolution time-of-flight data using Bayesian inference [PDF]

, 2019
The deconvolution of low-resolution time-of-flight data has numerous advantages, including the ability to extract additional information from the experimental data.
Bernardo J. M., Cornelius L. Pieterse, Hans C. Eggers, Mamyrin B. A., Michiel B. de Kock, Press W. H., R. J. Dwayne Miller, Wesley D. Robertson   +7 more
core   +2 more sources

Molecular composition of particulate matter emissions from dung and brushwood burning household cookstoves in Haryana, India [PDF]

, 2018
Emissions of airborne particles from biomass burning are a significant source of black carbon (BC) and brown carbon (BrC) in rural areas of developing countries where biomass is the predominant energy source for cooking and heating.
Arora, NK, Blake, DR, Edwards, RD, Fleming, LT, Laskin, A, Laskin, J, Lin, P, Meinardi, S, Nizkorodov, SA, Pillarisetti, A, Smith, KR, Weltman, R, Yadav, A   +12 more
core   +2 more sources

Using mass spectrometry imaging to map fluxes quantitatively in the tumor ecosystem

Nature Communications, 2023
Tumors are comprised of a multitude of cell types spanning different microenvironments. Mass spectrometry imaging (MSI) has the potential to identify metabolic patterns within the tumor ecosystem and surrounding tissues, but conventional workflows have ...
Michaela Schwaiger-Haber, Ethan Stancliffe, Dhanalakshmi S. Anbukumar, Blake Sells, Jia Yi, Kevin Cho, Kayla Adkins-Travis, Milan G. Chheda, Leah P. Shriver, Gary J. Patti   +9 more
doaj   +1 more source

Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level. [PDF]

, 2018
‘A picture is worth a thousand words’ is an idiom from the English language (‘borrowed’ from on old Chinese proverb) that conveys the notion that a complex idea can be succinctly and fully described by a single image. Never has this expression been truer
Andrén, PE, Caprioli, RM, Castellino, S, Charkoftaki, G, Duncan, MW, Goodwin, RJA, Johnson, CH, Rattray, NJW, Schey, KL, Shahidi-Latham, SK, Vasiliou, V, Veselkov, KA   +11 more
core   +3 more sources

Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI)

Toxicon: X, 2020
Amphibian cutaneous glands secrete toxins used in different vital functions including passive defense. Through Desorption Electrospray Ionization-Imaging we analyzed the distribution of the major toxins of the toad Rhinella marina parotoid macroglands ...
Pedro L. Mailho-Fontana, Andreia M. Porcari, Marcos N. Eberlin, Carlos Jared, Marta Maria Antoniazzi, Daniel C. Pimenta, Juliana M. Sciani   +6 more
doaj   +1 more source

Mass Spectrometry-based Methods for Phosphorylation Site Mapping of Hyperphosphorylated Proteins Applied to Net1, a Regulator of Exit from Mitosis in Yeast [PDF]

, 2002
Prior to anaphase in Saccharomyces cerevisiae, Cdc14 protein phosphatase is sequestered within the nucleolus and inhibited by Net1, a component of the RENT complex in budding yeast. During anaphase the RENT complex disassembles, allowing Cdc14 to migrate
Annan, Roland S., Carr, Steven A., Chen, Susan Loughery, Deshaies, Raymond J., Huddleston, Michael J., Shou, Wenying   +5 more
core   +1 more source

Proximity‐Induced Transfer of a Mass Tag Enables Direct Profiling of Active Matrix Metalloproteases

Angewandte Chemie, EarlyView.
A proximity‐induced, mass‐encoded activity‐based protein profiling (ABPP) approach transfers a MALDI‐detectable α‐cyano‐4‐hydroxycinnamic acid (CHCA) tag directly to active proteases. This tag enables the direct, multiplexed, and quantitative detection of enzyme activity in complex proteomes without enrichment or purification.
Lomane Berthy, Ugo Pasco, Mylene Sejalon‐Cipolla, Pierrick Bruyat, Monika Kaminska, Carole Malgorn, Fabrice Beau, Manca Osolin, Metka Novak, Barbara Breznik, Dimitris Georgiadis, Isabelle Correia, Emeline Groult, Olivier Lequin, Sarah Bregant, Yves‐Marie Pers, Daniele Noel, Robert Thai, Gilles Subra, Sonia Cantel, Laurent Devel   +20 more
wiley   +2 more sources

Mechanistic analysis of an asymmetric palladium-catalyzed conjugate addition of arylboronic acids to β-substituted cyclic enones. [PDF]

, 2015
An asymmetric palladium-catalyzed conjugate addition reaction of arylboronic acids to enone substrates was investigated mechanistically. Desorption electrospray ionization coupled to mass spectrometry was used to identify intermediates of the catalytic ...
Boeser, Cornelia L, Holder, Jeffrey C, Houk, KN, Stoltz, Brian M, Taylor, Buck LH, Zare, Richard N   +5 more
core   +3 more sources

Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism [PDF]

, 2020
Dysregulated cholesterol metabolism is implicated in a number of neurological disorders. Many sterols, including cholesterol and its precursors and metabolites, are biologically active and important for proper brain function. However, spatial cholesterol
Angelini, Roberto, Baumert, Mark, Clench, Malcolm, Griffiths, William J., Howell, Owain W., Mast, Natalia, Newton, Jillian, Pikuleva, Irina, Skibinski, David O.F., Wang, Yuqin, Yutuc, Eylan   +10 more
core   +2 more sources

Single-Cell Analysis and Its Applications by Surface Desorption Ambient Mass Spectrometry

Zhipu Xuebao
As the fundamental units of the structure and function of living organisms, cells perform the core functions of life activities. With the deepening research in life sciences, the importance of studies on cellular heterogeneity has become increasingly ...
Dan LIN, Xi-yang GE, Xin-er XING, Yong HE, Jin OUYANG, Na NA   +5 more
doaj   +1 more source