Results 61 to 70 of about 38,846 (279)

Three-Dimensional-Printed Lateral Extraction Enhanced Desorption Electrospray Ionization Source for Mass Spectrometry

Applied Sciences
This paper introduces a novel Lateral Extraction Enhanced Desorption Electrospray Ionization (LEE-DESI) source. This source is specifically designed to tackle the crucial issue of electric field interference in dual-channel ambient ionization mass ...
Jilin Liu, Xiang Qian
doaj   +1 more source

The foundations and development of lipidomics

Journal of Lipid Research, 2022
For over a century, the importance of lipid metabolism in biology was recognized but difficult to mechanistically understand due to the lack of sensitive and robust technologies for identification and quantification of lipid molecular species.
Xianlin Han, Richard W. Gross
doaj   +1 more source

Investigation and optimization of parameters affecting the multiply charged ion yield in AP-MALDI MS [PDF]

, 2016
Liquid matrix-assisted laser desorption/ionization (MALDI) allows the generation of predominantly multiply charged ions in atmospheric pressure (AP) MALDI ion sources for mass spectrometry (MS) analysis.
Boyle, Chowdhury, Cole, Cramer, Cramer, Dodonov, Dole, Douglas, Ehring, Fenn, Frankevich, Gillig, Glish, Good, Huang, Iribarne, Jeffery Brown, Kanu, Karas, Karas, Karas, Karas, Kebarle, Kellersberger, Kessner, Kim, Knochenmuss, Knochenmuss, Knochenmuss, König, Laiko, Li, Loboda, Makarov, Marshall, McEwen, Medzihradszky, Michael Morris, Miller, Mirgorodskaya, Navare, Page, Page, Pauly, Pavel Ryumin, Qin, Rainer Cramer, Ramanathan, Schneider, Syka, Takáts, Thomson, Trimpin, Westmacott, Whitehouse, Wolfender, Yamashita, Zenobi, Zerck, Zhou, Zubarev   +60 more
core   +1 more source

Long‐Tea‐CLIP: An Expert‐Level Multimodal AI Framework for Fine‐Grained Green Tea Grading Across Five Sensory Dimensions

Advanced Science, EarlyView.
Long‐Tea‐CLIP (Contrastive Language‐Image Pre‐training) presents a multimodal AI framework that integrates visual, metabolomic, and sensory knowledge to grade green tea across appearance, soup color, aroma, taste, and infused leaf. By combining expert‐guided modeling with CLIP‐supervised learning, the system delivers fine‐grained quality evaluation and
Yanqun Xu, Zhengfang Xue, Qing Luo, Xu Liu, Yongquan Xu, Jing Huang, Xingcai Zhang, Xinyuan Zhang, Zhonghua Liu, Zisheng Luo   +9 more
wiley   +1 more source

Ambient DESI and LESA-MS analysis of proteins adsorbed to a biomaterial surface using in-situ surface tryptic digestion [PDF]

, 2013
The detection and identification of proteins adsorbed onto biomaterial surfaces under ambient conditions has significant experimental advantages but has proven to be difficult to achieve with conventional measuring technologies. In this study, we present
Alexander, Morgan R., Barrett, David A., Celiz, Adam D., Rao, Wei, Scurr, David J.   +4 more
core   +3 more sources

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li   +15 more
wiley   +1 more source

Characterization of Cell Glycocalyx with Mass Spectrometry Methods. [PDF]

, 2019
The cell membrane plays an important role in protecting the cell from its extracellular environment. As such, extensive work has been devoted to studying its structure and function.
Lebrilla, Carlito B, Li, Qiongyu, Wong, Maurice, Xie, Yixuan   +3 more
core   +2 more sources

A Combined Desorption Ionization by Charge Exchange (DICE) and Desorption Electrospray Ionization (DESI) Source for Mass Spectrometry [PDF]

Journal of the American Society for Mass Spectrometry, 2011
A source that couples the desorption ionization by charge exchange (DICE) and desorption electrospray ionization (DESI) techniques together was demonstrated to broaden the range of compounds that can be analyzed in a single mass spectrometric experiment under ambient conditions. A tee union was used to mix the spray reagents into a partially immiscible
Chang-Ching, Chan, Mark S, Bolgar, Scott A, Miller, Athula B, Attygalle   +3 more
openaire   +2 more sources

Polar Lattice‐Distorted Motifs Enable Synergy of Local Polarization/Dipole Fields for Concurrent Glyphosate Wastewater Remediation and CO Evolution

Advanced Science, EarlyView.
Photocatalytic treatment of glyphosate herbicide in agricultural wastewater is achieved through the cooperative effect of the local polarization field and dipole field mediated by lattice‐distorted carbon nitride. Glyphosate is completely degraded via selective C─P bond cleavage with a CO evolution rate of 1166 µmol g−1 h−1.
Daoping Chen, Huan Liu, Tengyu Liu, Jie Li, Qizhi Luo, Yan Zhang, Shengkun Li, Hu Li   +7 more
wiley   +1 more source

Metabolite fingerprinting by infrared matrix-assisted laser desorption electrospray ionization mass spectrometry

SLAS Technology
The adoption of mass spectrometry for high-throughput screening in drug discovery has become increasingly prevalent and has enabled label-free screening against diverse targets.
Alena N. Joignant, Fan Pu, Shaun M. McLoughlin, James W. Sawicki, Andrew J. Radosevich, Renze Ma, Jon D. Williams, Sujatha M. Gopalakrishnan, Nathaniel L. Elsen   +8 more
doaj   +1 more source