Results 81 to 90 of about 16,991 (224)

Liquid Atmospheric Pressure MALDI (LAP‐MALDI) Mass Spectrometry: A Versatile Tool for the Characterization of Synthetic Polymers

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 16, 30 August 2026.
ABSTRACT Rationale Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) has previously been applied to the analysis of biopolymers such as peptides, proteins, and DNA, producing ESI‐like multiply charged analyte ions.
Agata E. Kowalczyk   +3 more
wiley   +1 more source

Solid-Phase Extraction Strategies to Surmount Body Fluid Sample Complexity in High-Throughput Mass Spectrometry-Based Proteomics

open access: yesJournal of Analytical Methods in Chemistry, 2015
For large-scale and standardized applications in mass spectrometry- (MS-) based proteomics automation of each step is essential. Here we present high-throughput sample preparation solutions for balancing the speed of current MS-acquisitions and the time ...
Marco R. Bladergroen   +1 more
doaj   +1 more source

Enhancing IR‐MALDESI MSI Spatial Resolution Through Beam Constriction With a Ring‐Actuated Iris

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 16, 30 August 2026.
ABSTRACT Rationale Infrared matrix‐assisted laser desorption electrospray ionization (IR‐MALDESI) mass spectrometry imaging (MSI) enables label‐free, spatially resolved molecular analysis of biological tissues under ambient conditions. While improving spatial resolution is important for mapping fine tissue structures, mid‐infrared (IR) lasers are ...
Sarah M. Ashbacher   +6 more
wiley   +1 more source

FT-ICR-MS approach to monitor asparagine deamidation and its isomers products in collagen from ancient bones [PDF]

open access: yes
This project investigates the use of ultrahigh resolution mass spectrometry along with fragmentation techniques such as electron capture dissociation (ECD) and collisionally activated dissociation (CAD) to study deamidation of ancient bone, by using ...
Perez Hurtado, Pilar
core  

Dehydration‐driven organization of metabolites into NaDES‐like assemblies in orthodox seeds

open access: yesNew Phytologist, Volume 251, Issue 3, Page 1172-1187, August 2026.
Summary Desiccation tolerance in plants, especially during orthodox seed dehydration, relies on compatible solute accumulation, complex molecular mechanisms, and intermolecular organizations that remain poorly understood. We combined metabolite profiling, mass spectrometry imaging, and electrospray and cold‐spray ionization mass spectrometry to ...
Youcef Haddad   +11 more
wiley   +1 more source

Use of analytical strategies to understand spatial chemical variation in bacterial surface communities

open access: yesJournal of Bacteriology
Not only do surface-growing microbes such as biofilms display specific traits compared to planktonic cells, but also they display many heterogeneous behaviors over many spatial and temporal contexts.
Abigail A. Weaver, Joshua D. Shrout
doaj   +1 more source

Advancing proteomics with ion/ion chemistry Mass Spectrometry For Proteomics Analysis

open access: yesBioTechniques, 2006
Mass spectrometers, instruments that use electric and/or magnetic fields to measure a gas-phase ion's mass-to-charge ratio (m/z), are used in a wide variety of applications—with the field having a reputation for providing good sensitivity and high ...
David M. Good, Joshua J. Coon
doaj   +1 more source

Deep Learning Sensing Platform for Simultaneous Detection of Kanamycin and Kanamycin B Based on Dual‐Recognition and Catalytic Modulation Mechanism of Aptamer‐Functionalized MIL‐101 Nanozyme

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Schematic illustration of the deep learning‐based sensing platform for simultaneous detection of KAN and KMB, constructed through dual recognition and catalytic modulation mechanisms of the aptamer‐functionalized MIL‐101 nanozyme. ABSTRACT Extensive antibiotic use has raised concerns over residues in food, necessitating rapid and accurate detection ...
Yadi Qin   +5 more
wiley   +1 more source

High mass accuracy analytical applications of Fourier transform ion cyclotron resonance mass spectrometry [PDF]

open access: yes
The performance capabilities of Fourier transform ion cyclotron resonance (FTICR) mass spectrometry are higher than any other type of mass spectrometer, making this technique suitable for a range of analytical applications.
Wills, Rebecca Helen
core  

Manipulation of Protein Charge States through Continuous Flow-Extractive Desorption Electrospray Ionization: A New Ambient Ionization Technique

open access: yes, 2016
Manipulation of protein charge states in electrospray ionization-mass spectrometry (ESI-MS) has implications for the study of intact proteins, protein−protein interactions, post-translational modifications, and protein sequencing.
Brian L. Edwards (1943161)   +4 more
core   +1 more source

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