Results 51 to 60 of about 376,084 (233)

Bioorthogonal Click‐to‐Disassemble Phthalocyanine Nanoassemblies for Precise Chemo‐Photodynamic Therapy against Hypoxic Tumors

open access: yesAdvanced Science, EarlyView.
A bioorthogonal “click‐to‐disassemble” strategy enables precise activation of self‐assembled phthalocyanine nanoassemblies for chemo‐photodynamic therapy. EGFR‐targeted activator triggers IEDDA‐mediated disruption of the quenched assemblies, restoring fluorescence and ROS generation while releasing tirapazamine.
Jiaxin Shen   +4 more
wiley   +1 more source

Correction to VAMAS Interlaboratory Study for Desorption Electrospray Ionization Mass Spectrometry (DESI MS) Intensity Repeatability and Constancy

open access: yes, 2016
Correction to VAMAS Interlaboratory Study for Desorption Electrospray Ionization Mass Spectrometry (DESI MS) Intensity Repeatability and ...
Paulina D. Rakowska (1718956)   +5 more
core   +1 more source

A Single‐Capillary Open Microfluidic Probe for Robust and Versatile Spatial Multi‐Omics Using Ambient Mass Spectrometry Imaging

open access: yesAdvanced Science, EarlyView.
This study reports a knot‐shaped single‐capillary open microfluidic probe (Knot‐probe) for robust and versatile spatial omics, enabling ambient mass spectrometry imaging with high spatial resolution, throughput, and structure‐resolved capability. Knot‐probe mitigates the trade‐off between analytical performance and operational robustness, providing an ...
Xiangyu Zhu   +10 more
wiley   +1 more source

Imaging regiospecific lipid turnover in mouse brain with desorption electrospray ionization mass spectrometry[S]

open access: yesJournal of Lipid Research, 2017
Compartmentalization of metabolism into specific regions of the cell, tissue, and organ is critical to life for all organisms. Mass spectrometric imaging techniques have been valuable in identifying and quantifying concentrations of metabolites in ...
Richard H. Carson   +7 more
doaj   +1 more source

Application of Mass Spectrometry Imaging for Visualizing Food Components

open access: yesFoods, 2020
Consuming food is essential for survival, maintaining health, and triggering positive emotions like pleasure. One of the factors that drive us toward such behavior is the presence of various compounds in foods.
Yukihiro Yoshimura, Nobuhiro Zaima
doaj   +1 more source

Evaluation of Quantitative Platforms for Single Target Mass Spectrometry Imaging

open access: yesPharmaceuticals, 2022
(1) Imaging of pharmaceutical compounds in tissue is an increasingly important subsection of Mass Spectrometry Imaging (MSI). Identifying proper target engagement requires MS platforms with high sensitivity and spatial resolution.
Andrew P. Bowman   +5 more
doaj   +1 more source

Nanospray Desorption Electrospray Ionization (nano-DESI) Mass Spectrometry Imaging of Drift Time-Separated Ions [PDF]

open access: yes, 2020
Simultaneous spatial localization and structural characterization of molecules in complex biological samples currently represents an analytical challenge for mass spectrometry imaging (MSI) techniques.
ruichuan, yin   +6 more
core   +1 more source

Evaluation of Formalin-Fixed and FFPE Tissues for Spatially Resolved Metabolomics and Drug Distribution Studies

open access: yesPharmaceuticals, 2022
Fixation of samples is broadly used prior to the histological evaluation of tissue samples. Though recent reports demonstrated the ability to use fixed tissues for mass spectrometry imaging (MSI) based proteomics, glycomics and tumor classification ...
Andreas Dannhorn   +7 more
doaj   +1 more source

Accelerating green heterocyclic synthesis: Convergence of AI, automation, and sustainable chemistry

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Green heterocyclic synthesis and data‐driven tools such as AI, high‐throughput experimentation, continuous flow, and self‐driving laboratories have developed largely in parallel. This review connects them and asks how green metrics such as E‐factor and PMI might serve as explicit optimization targets rather than post‐hoc measures, toward sustainable ...
Noor Aisyah Ahmad Shah   +8 more
wiley   +1 more source

Designing and Construction of Thermal Desorption and Ionization Units for Ambient Ionization Mass Spectrometry

open access: yes, 2023
Ambient Ionization Mass Spectrometry(AIMS) is a technique used for ionization and analysis in atmosphere. Analytes can be analyzed without complex preprocessing steps, facilitating rapid detection and high-throughput analysis.
Ko, Kuan-Yu
core  

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