Results 51 to 60 of about 16,991 (224)

Metabolite fingerprinting by infrared matrix-assisted laser desorption electrospray ionization mass spectrometry

SLAS Technology
The adoption of mass spectrometry for high-throughput screening in drug discovery has become increasingly prevalent and has enabled label-free screening against diverse targets.
Alena N. Joignant, Fan Pu, Shaun M. McLoughlin, James W. Sawicki, Andrew J. Radosevich, Renze Ma, Jon D. Williams, Sujatha M. Gopalakrishnan, Nathaniel L. Elsen   +8 more
doaj   +1 more source

A Combined Desorption Ionization by Charge Exchange (DICE) and Desorption Electrospray Ionization (DESI) Source for Mass Spectrometry [PDF]

Journal of the American Society for Mass Spectrometry, 2011
A source that couples the desorption ionization by charge exchange (DICE) and desorption electrospray ionization (DESI) techniques together was demonstrated to broaden the range of compounds that can be analyzed in a single mass spectrometric experiment under ambient conditions. A tee union was used to mix the spray reagents into a partially immiscible
Chang-Ching, Chan, Mark S, Bolgar, Scott A, Miller, Athula B, Attygalle   +3 more
openaire   +2 more sources

Analytical Approaches to Address Challenges in the Analysis of Cannabinoids in Vascular Matrices Using Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Phytocannabinoids are bioactive metabolites derived from the Cannabis sativa plant. They have garnered attention due to their recreational uses and therapeutic potential. Although various analytical strategies have been employed for their analysis, mass spectrometry (MS) coupled to chromatographic separation is superior due to its sensitivity ...
Radwa Mahmoud, Robert B. Laprairie, Anas El‐Aneed   +2 more
wiley   +1 more source

Imaging of Human Lens Lipids by Desorption Electrospray Ionization Mass Spectrometry [PDF]

, 2010
The lipid composition of the human lens is distinct from most other tissues in that it is high in dihydrosphingomyelin and the most abundant glycerophospholipids in the lens are unusual 1-O-alkyl-ether linked phosphatidylethanolamines and ...
Wu, C., Mitchell, T. W., Cooks, R. Graham, Deeley, J. M., Todd W. Mitchell, Chunping Wu, R. Graham Cooks, Panhuis, M. I. H., Panhuis, Marc in het, Xiangjia Zhu, Zhu, Xiangjia, Zhu, X., Roger J. W. Truscott, Truscott, R. J. W., Cooks, R. G., Truscott, Roger J.W., Wu, Chunping, Shane R. Ellis, Stephen J. Blanksbya, Ellis, Shane R., Mitchell, Todd W., Jane M. Deeley, Deeley, Jane M., Marc in het Panhuis, Ellis, S. R., Blanksby, Stephen J.   +25 more
core   +1 more source

Chemical Ionization Mass Spectrometry: Fundamental Principles, Diverse Applications, and the Latest Technological Frontiers

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt, Adriana Arigò, Giorgio Famiglini, Pierangela Palma, Achille Cappiello   +4 more
wiley   +1 more source

Study of Electrochemical Reactions Using Nanospray Desorption Electrospray Ionization Mass Spectrometry

, 2016
The combination of electrochemistry (EC) and mass spectrometry (MS) is a powerful analytical tool for studying mechanisms of redox reactions, identification of products and intermediates, and online derivatization/recognition of analytes.
Pengyuan Liu (32609), Howard D. Dewald (2068474), Hao Chen (5190), Julia Laskin (1354860), Ingela T. Lanekoff (2068471)   +4 more
core   +1 more source

Trace-Level Screening of Chemicals Related to Clandestine Desomorphine Production with Ambient Sampling, Portable Mass Spectrometry

Journal of Chemistry, 2017
Desomorphine is a semisynthetic opioid that is responsible for the psychoactive effects of a dangerous homemade injectable mixture that goes by street name “Krokodil.” Desorption electrospray ionization (DESI) and paper spray ionization (PSI) are ...
Seth E. Hall, Adam E. O’Leary, Zachary E. Lawton, Alessandra M. Bruno, Christopher C. Mulligan   +4 more
doaj   +1 more source

The application of mass spectrometry imaging in traditional Chinese medicine: a review

Chinese Medicine, 2022
Mass spectrometry imaging is a frontier technique which connects classical mass spectrometry with ion imaging. Various types of chemicals could be visualized in their native tissues using mass spectrometry imaging.
Lieyan Huang, Lixing Nie, Zhong Dai, Jing Dong, Xiaofei Jia, Xuexin Yang, Lingwen Yao, Shuang-cheng Ma   +7 more
doaj   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Matrix- and Surface-Assisted Laser Desorption/Ionization Mass Spectrometry Methods for Urological Cancer Biomarker Discovery—Metabolomics and Lipidomics Approaches

Metabolites
Urinary tract cancers, including those of the bladder, the kidneys, and the prostate, represent over 12% of all cancers, with significant global incidence and mortality rates.
Adrian Arendowski
doaj   +1 more source