Results 221 to 230 of about 128,340 (290)

Identification of Natural Isonitriles Through Ligation to an Azomethine Imine Probe

open access: yesChemistry – A European Journal, EarlyView.
The azomethine imine (AMI)–isonitrile (NC) ligation allowed for the chemoselective detection of natural isonitriles in bacteria and fungi. The reactivity‐based screening establishes a new stereogenic center, thereby allowing for facile distinction between chiral and achiral isonitriles. The work also unraveled a unique reactivity of isonitriles bearing
Maurice P. Biedermann   +6 more
wiley   +1 more source

Detection of IDH mutation in glioma by desorption electrospray ionization (DESI) tandem mass spectrometry. [PDF]

open access: yesSci Rep
Shahi M   +5 more
europepmc   +1 more source

Photocatalytic Degradation of PFOA with Porous Lanthanoid Perovskites Nano Catalyst

open access: yesChemie Ingenieur Technik, EarlyView.
Photocatalytic degradation of PFOA was studied using nickel‐ and lanthanide‐doped perovskites under UV–VIS irradiation. Catalyst characterization confirmed successful doping, with Ni/NdMnO3 showing the highest photocatalytic efficiency. Degradation occurred via C–C bond cleavage, forming transformation products PFHpA and PFHxA.
Julia Schowarte   +5 more
wiley   +1 more source

Characterization of Anticancer Drug Protomers Using Electrospray Ionization and Ion Mobility Spectrometry-Mass Spectrometry. [PDF]

open access: yesJ Am Soc Mass Spectrom
Basuri P   +6 more
europepmc   +1 more source

Supercritical water deasphalting and desulphurization of heavy fuel oil with comprehensive molecular‐level analysis and techno‐economic analysis

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Supercritical water deasphalting. Abstract The removal of sulphur from heavy fuel oil (HFO) is essential to address environmental concerns and comply with the stringent regulations imposed by the International Maritime Organization (IMO) in 2020. Previously, the acceptable limit for sulphur was 3.5 wt.%, but it was recently changed to 0.5 wt.%.
Biswajit Saha   +6 more
wiley   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen   +2 more
wiley   +1 more source

Effects of High‐ and Low‐Fat Meals on the Bioavailability and Pharmacokinetics of Votoplam, a HTT Gene Splicing Modifier

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee   +5 more
wiley   +1 more source

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