Results 251 to 260 of about 142,148 (337)

Mitochondria‐Catalyzed Activation of Anticancer Prodrugs

ChemCatChem, EarlyView.
Prodrug C is a water soluble, monomeric compound accumulating in mitochondria of cancer cells, where it is activated in the reaction with mitochondrial H2O2. The activation leads to the release of camptothecin that causes cell cycle arrest in G2 phase and cancer cell death.
Michael Raucheisen, Dina Attia, Marlies Körber, Alejandra Aroca Crevillén, Andrés Hidalgo, Frank Beierlein, Petra Imhof, Andriy Mokhir   +7 more
wiley   +1 more source

Desorption Electrospray Ionization Cyclic Ion Mobility-Mass Spectrometry Imaging for Traumatic Brain Injury Spatial Metabolomics. [PDF]

Anal Chem
Leontyev D, Olivos H, Shrestha B, Datta Roy PM, LaPlaca MC, Fernández FM.   +5 more
europepmc   +1 more source

Palladium‐Catalyzed Allylation of (Hetero)Aryl Fluorosulfates

ChemCatChem, EarlyView.
The palladium‐catalyzed allylation of (hetero)aryl fluorosulfates is described using either allyl pinacolboronate or potassium allyltrifluoroborate as the allyl source, thereby affording allyl‐(hetero)arene products in synthetically useful isolated yields, including examples featuring potentially reactive chloro groups.
Kathleen M. Morrison, Joshua W. M. MacMillan, Annie M. Martell, Giulio Volpin, Sherif J. Kaldas, Philipp M. Holstein, Maximilian Lübbesmeyer, Mark James Ford, Nicolas Guimond, Mark Stradiotto   +9 more
wiley   +1 more source

Compositional Characterization of Syngas-Based Glycolide Using Gas Chromatogram-Mass Spectrometry and Electrospray Ionization High-Resolution Mass Spectrometry. [PDF]

Molecules
Zhang Y, Chen J, He J, Li S, Wang Y, Zhang Y, Shi Q.   +6 more
europepmc   +1 more source

Determination of Cabergoline by Electrospray Ionization Tandem Mass Spectrometry: Picogram Detection via Column Focusing Sample Introduction

, 2001
Bruce A. Kimball, Thomas J. DeLiberto, John J. Johnston   +2 more
openalex   +2 more sources

AzUlene‐Fused Polycyclic Aromatic Hydrocarbons: Synthesis, Structural, Optical, and Electrochemical Properties of Azuleno[2,1‐a]phenalenones

ChemistryEurope, EarlyView.
Delving into the synthesis of azulene‐fused polycyclic aromatic hydrocarbons, this article presents an effective route via Suzuki–Miyaura coupling and Brønsted acid‐mediated cyclization. It details unique optical properties, that is, UV/vis and fluorescence spectra, and electrochemical behavior, highlighting remarkable halochromism and electrochromism ...
Taku Shoji, Naoko Sakata, Ryunosuke Ishikawa, Shigeki Mori, Tetsuo Okujima, Ryuta Sekiguchi, Shunji Ito   +6 more
wiley   +1 more source

Introduction of a Phosphine Group onto the Ferrocene Moiety in Ferrociphenol Opens Access to New Heterobimetallic Complexes with Anticancer Activity

ChemistryEurope, EarlyView.
Modification of the ferrociphenol structure by a phosphine moiety appended to the originally unsubstituted cyclopentadienyl ring of the ferrocene unit represents a new and useful modification of this potent anticancer agent and opens a way to the preparation of new biologically active derivatives (e.g., phosphonium salts) and, mainly, heterobimetallic ...
Magda Křelinová, Michèle Salmain, Petr Štěpnička, Ivana Císařová, Benoît Bertrand, Jiří Schulz   +5 more
wiley   +1 more source

Self‐Assembly of Silver Nanoclusters by Cooperative Acetylene Bonding with Mutual Pyridyl Coordination

ChemistryEurope, EarlyView.
A strategy for the hierarchical self‐assembly of an emissive silver nanocluster into a 3D crystalline lattice via cooperative acetylene bonding in concert with networking silver···pyridyl coordination embodying the hexadentate form is demonstrated. The controlled supramolecular alignment of atomically precise metal nanoclusters is a promising method to
Tasuki Tsurumi, Takahiro Nakagawa, Takashi Kikuchi, Kiyohiro Adachi, Hironobu Hayashi, Atsuro Takai, Takuma Kaneko, Tomoya Uruga, Daisuke Hashizume, Yosuke Nakamura, Makoto Fujita, Yuya Domoto   +11 more
wiley   +1 more source

Pulsed Nano-Electrospray Ionization Applied to Solutions of Angiotensin II, Bradykinin, and Gramicidin S in Water/Acetonitrile (1/1) with the Addition of 1% Acetic Acid and 10 mM Ammonium Acetate. [PDF]

Mass Spectrom (Tokyo)
Hiraoka K, Usmanov DT, Ninomiya S, Rankin-Turner S, Akashi S.   +4 more
europepmc   +1 more source

Mono‐Ethyl‐Phosphonates: Functional Group Masking Strategy to Stabilize and Optimize the Pharmacokinetics of Rare Earth Radiochelates

ChemistryEurope, EarlyView.
Prodrug strategies are used to enhance the pharmacokinetics of small molecule drugs. Here, this approach to rare earth coordination complexes is adopted with applications as diagnostic and therapeutic radiopharmaceuticals: a mono‐ethyl‐phosphonate polyazamacrocyclic chelator for 44Sc and 177Lu reduces blood and bone uptake.
Jennifer N. Whetter, Axia Marlin, Edith K. Amason, Eduardo Aluicio‐Sarduy, Angus J. Koller, Phuong Nguyen Tran, Kaelyn V. Becker, Jonathan W. Engle, Eszter Boros   +8 more
wiley   +1 more source