Results 261 to 270 of about 230,711 (334)

Detection of IDH mutation in glioma by desorption electrospray ionization (DESI) tandem mass spectrometry. [PDF]

open access: yesSci Rep
Shahi M   +5 more
europepmc   +1 more source

Intact Mass Profiling Reveals Phospho‐Proteoforms of the Catenins (85–110 kDa) Regulated by Actomyosin Contractility

open access: yesAngewandte Chemie, EarlyView.
This study advances top‐down individual ion mass spectrometry (I2MS) to profile intact phospho‐proteoforms of β‐ and α‐catenins (85–110 kDa) within cadherin–catenin complexes. By modulating actomyosin contractility, we reveal mechano‐sensitive phosphorylation patterns and propose that distinct catenin proteoforms may reflect adhesive states at cell ...
Che‐Fan Huang   +4 more
wiley   +2 more sources

A Triple Threat Against Ovarian Cancer: Os(II)‐Pt(IV)‐Ceritinib Conjugates for Photodynamic Therapy, Chemotherapy, and Immunogenic Cell Death Induction

open access: yesAngewandte Chemie, EarlyView.
A novel Os(II)‐Pt(IV)‐Ceritinib (Os‐Pt‐Cer) conjugate enables triple‐action anticancer therapy by integrating photodynamic therapy, chemotherapy, and immunogenic cell death (ICD) induction into a single molecule. Upon near‐infrared light activation, this heterobimetallic complex exhibits potent antiproliferative effects in ovarian cancer models ...
Marta Redrado   +10 more
wiley   +2 more sources

Characterization of Anticancer Drug Protomers Using Electrospray Ionization and Ion Mobility Spectrometry-Mass Spectrometry. [PDF]

open access: yesJ Am Soc Mass Spectrom
Basuri P   +6 more
europepmc   +1 more source

Design and Structural Transformations of Zinc(II) Knotted Cage Frameworks

open access: yesAngewandte Chemie, EarlyView.
Systematic control over coordination environments and subcomponent sequences enabled the formation and stabilization of trefoil perplexanes and trefoil tetrahedral knotted cages. Peripheral crosslinkers diminished framework stability to tune host–guest behavior and dynamic exchange, while mechanical entanglement modulated self‐sorting and guest binding,
Yuchong Yang   +7 more
wiley   +2 more sources

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