Results 281 to 290 of about 204,339 (353)

Dinuclear Rhodium(I)–N‐Heterocyclic Carbene Complexes as Alkyne Hydropyridonation Catalysts

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
Catalyst Improvement by NHC tuning: A series of new RhI–NHC dinuclear complexes has been revealed as efficient alkyne hydropyridonation catalysts. 333053IMes complex displays the highest reactivity of the series, suggesting that a moderate steric demand combined with balanced σ‐donation facilitates precatalyst activation and substrate exchange.
Belinda Español‐Sánchez   +7 more
wiley   +1 more source

Study of Uncatalyzed and Micellar‐Catalyzed Oxidative Degradation of Amoxicillin by Colloidal MnO2: Experimental Optimization and Mechanistic Aspects

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The absorption spectra of amoxicillin degradation by colloidal MnO2 in the presence and absence of surfactants. Herein, the oxidative degradation of amoxicillin (AMX) by water‐soluble colloidal MnO2 is investigated spectrophotometrically at 298 K in both uncatalyzed and nonionic micellar‐catalyzed media (Triton X‐100 and Brij‐35).
Neelam Sen   +4 more
wiley   +1 more source

Sustainability in Analytical Chemistry Illustrated by Pharmaceutical Nitrosamine Testing

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Following the valsartan scandal in 2018, the testing of drug substances and drug products for N‐nitrosamines has become a critical and mandatory quality control measure. The European Pharmacopoeia chapter 2.5.42 currently describes three analytical methods for this purpose: HPLC–MS/MS, GC–MS, and GC–MS/MS.
Felix Bredendiek   +2 more
wiley   +1 more source

Enantioselective Determination of Amphetamine‐Type Stimulants in Environmental Waters Using SPE and CE–MS/MS

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT The growing concern over drug abuse, particularly involving amphetamine‐type substances (ATS), has led to their monitoring in environmental waters. These chiral compounds, commonly found in river water and wastewater treatment plant (WWTP) effluents, require analytical methods capable of enantiomeric discrimination, as their enantiomers can ...
Pol Clivillé‐Cabré   +3 more
wiley   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk   +4 more
wiley   +1 more source

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