Results 1 to 10 of about 149,784 (296)

Electrospray Ionization-Induced Protein Unfolding [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2012
Electrospray ionization mass spectrometry (ESI-MS) measurements were performed under a variety of solution conditions on a highly acidic sub-fragment (B3C) of the C-terminal carbohydrate-binding repeat region of Clostridium difficile toxin B, and two mutants (B4A and B4B) containing fewer acidic residues.
Kenneth K S Ng   +2 more
exaly   +5 more sources

Principles of Electrospray Ionization [PDF]

open access: yesMolecular & Cellular Proteomics, 2011
Electrospray ionization is today the most widely used ionization technique in chemical and biochemical analysis. Interfaced with a mass spectrometer it allows the investigation of the molecular composition of liquid samples. With electrospray a large variety of chemical substances can be ionized.
Matthias Wilm, Wilm, Matthias, M. Wilm
openaire   +8 more sources

Some Thoughts on Electrospray Ionization Mechanisms

open access: yesEuropean Journal of Mass Spectrometry, 2011
Electrospray ionization (ESI) mechanisms are highly complex, due to a series of physical and chemical phenomena taking place on a complex system, as a solution is. In fact, even if the solution of an analyte in a protic medium can be considered at first sight to be a two-component system, the presence of solvent dissociation ...
Sara Crotti, Pietro Traldi
exaly   +5 more sources

Transmission mode desorption electrospray ionization [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2008
A new mode of operation for desorption electrospray ionization (DESI) analysis of liquids or solid residues from evaporated solvents is presented. Unlike traditional DESI, the electrospray is not deflected off of a surface but instead is transmitted through a sampling mesh at a 0 degrees angle between the electrospray tip, sample mesh, and capillary ...
Chipuk, Joseph E., Brodbelt, Jennifer S.
openaire   +4 more sources

Comparison of Mass Spectrometry Imaging by Desorption Electrospray Ionization (DESI) and Desorption Electro-Flow Focusing Ionization (DEFFI) [PDF]

open access: yesMetabolites
Background: Among atmospheric-pressure mass spectrometry imaging (MSI) methods, desorption electrospray ionization (DESI) and desorption electro-flow focusing ionization (DEFFI) represent cost-effective, high-throughput approaches that utilize ...
Yunshuo Tian   +3 more
doaj   +2 more sources

Nanobubbles in Electrospray Ionization Mass Spectrometry. [PDF]

open access: yesAnal Chem
Nanobubbles (NBs) are very small gas-filled cavities in solvents, and when their sizes reach diameters around 200 nm, they remain in solution for extended periods of time, featuring special chemical and physical properties. Here, we investigate the application of NBs in electrospray ionization.
Joseph G, Binny B, Venter AR.
europepmc   +3 more sources

Mechanistic investigation of ionization suppression in electrospray ionization [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2000
We show results from experiments designed to determine the relative importance of gas phase processes and solution phase processes into ionization suppression observed in biological sample extracts. The data indicate that gas phase reactions leading to the loss of net charge on the analyte is not likely to be the most important process involved in ...
King, Richard   +4 more
openaire   +3 more sources

A:Recent advances in ambient electrospray ionization technologies [PDF]

open access: yesRecords of Pharmaceutical & Biomedical Sciences, 2020
Mass spectrometry is one of the most powerful techniques for detection and identification. Due to its sensitivity and selectivity, exact mass of analytes, and in effect, their relative fragments, allow for total structure information.
Sara Amer   +6 more
doaj   +1 more source

Extractive electrospray ionization mass spectrometry for analytical evaluation and synthetic preparation of pharmaceutical chemicals

open access: yesFrontiers in Pharmacology, 2023
Extraction electrospray ionization mass spectrometry (EESI-MS), due to the unique configuration of its ionization module, enables the effective ionization of trace molecules of interest in samples containing complex matrices with high sensitivity, high ...
Manman Qin   +9 more
doaj   +1 more source

Basic principle from electrospray ionization to soft ionization mass spectrometry and development of ion source [PDF]

open access: yes, 2023
Since the electrospray phenomenon was discovered, there is still an unsolved mystery about the prinple of generating charged analyte in the soft ionization phenomenon which represented by ESI.
jiehong, luo
core   +1 more source

Home - About - Disclaimer - Privacy