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Extractive Electrospray Ionization Mass Spectrometry for Analytical Evaluation and Synthetic Preparation of Pharmaceutical Chemicals

open access: yesFrontiers in Pharmacology, 2023
Extraction electrospray ionization mass spectrometry (EESI-MS), due to the unique configuration of its ionization module, enables the effective ionization of trace molecules of interest in samples containing complex matrices with high sensitivity, high ...
Huanwen Chen, Yuqing Qian
exaly   +3 more sources

Some Thoughts on Electrospray Ionization Mechanisms

open access: yesEuropean Journal of Mass Spectrometry, 2011
Electrospray ionization (ESI) mechanisms are highly complex, due to a series of physical and chemical phenomena taking place on a complex system, as a solution is. In fact, even if the solution of an analyte in a protic medium can be considered at first sight to be a two-component system, the presence of solvent dissociation ...
Sara Crotti, Pietro Traldi
exaly   +5 more sources

A:Recent advances in ambient electrospray ionization technologies [PDF]

open access: yesRecords of Pharmaceutical & Biomedical Sciences, 2020
Mass spectrometry is one of the most powerful techniques for detection and identification. Due to its sensitivity and selectivity, exact mass of analytes, and in effect, their relative fragments, allow for total structure information.
Sara Amer   +6 more
doaj   +1 more source

Enhancing Metabolomic Coverage in Positive Ionization Mode Using Dicationic Reagents by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

open access: yesMetabolites, 2021
Mass spectrometry imaging is a powerful tool to analyze a large number of metabolites with their spatial coordinates collected throughout the sample. However, the significant differences in ionization efficiency pose a big challenge to metabolomic mass ...
Ying Xi, David C. Muddiman
doaj   +1 more source

Efficiency of nano-electrospray ionization [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2005
The efficiency of nano-electrospray ionization, defined as the flux of ions reaching the detector of a triple-quadrupole mass spectrometer divided by the flux of analyte ions leaving the needle, has been measured in a series of controlled experiments with dodecyltrimethyl ammonium (DDTMA) bromide, myoglobin, Glu- [1]-fibrinopeptide, and gramicidin S ...
El-Faramawy, Ayman   +2 more
openaire   +2 more sources

Research Progress of Highly Selective Solid Substrate Electrospray Ionization Sources for Mass Spectrometry [PDF]

open access: yesZhipu Xuebao, 2022
Solid substrate electrospray mass spectrometry is an ambient mass spectrometry method that involves carrying, ionization and detection of the samples. This approach has a wide range of applications, and which is appropriate for rapid mass spectrometric ...
ZHANG Feng;MU Guo-dong;LIU Tong
doaj  

Implementation of a MS/MS database for isoquinoline alkaloids and other annonaceous metabolites

open access: yesScientific Data, 2022
Measurement(s) electrospray ionization Technology Type(s) Ultra High-performance Liquid Chromatography • Tandem Mass ...
Salemon Akpa Agnès   +12 more
doaj   +1 more source

Exploiting the formation of adducts in mobile phases with ammonium fluoride for the enhancement of annotation in liquid chromatography-high resolution mass spectrometry based lipidomics

open access: yesJournal of Chromatography Open, 2021
Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS) based lipidomics has become the most versatile analytical tool to discover and detect lipids using a non-targeted approach.
Carolina Gonzalez-Riano   +2 more
doaj   +1 more source

Development and Performance Test of Enclosed Extractive Electrospray Ionization Device [PDF]

open access: yesZhipu Xuebao, 2023
Extractive electrospray ionization (EESI) technology has the advantages of directly ionizing the target molecules in the samples without complex sample pretreatments, and it is widely used for analysis of complex matrix samples, especially for aerosol ...
DONG Xiao-feng1   +4 more
doaj   +1 more source

Desorption Electrospray Ionization (DESI) Mass Spectrometric Imaging of the Distribution of Rohitukine in the Seedling of Dysoxylum binectariferum Hook. F. [PDF]

open access: yesPLoS ONE, 2016
Ambient ionization mass spectrometric imaging of all parts of the seedling of Dysoxylum binectariferum Hook. f (Meliaceae) was performed to reconstruct the molecular distribution of rohitukine (Rh) and related compounds.
Patel Mohana Kumara   +5 more
doaj   +1 more source

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