Results 221 to 230 of about 260,257 (350)

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg, Tanja M. Gampfer, Lea Wagmann, Philip Schippers, Jennifer Herrmann, Rolf Müller, Folker Westphal, Markus R. Meyer   +7 more
wiley   +1 more source

Understanding the influence of transfusion and blood loss on tranexamic acid concentration in scoliosis surgery with blood loss

British Journal of Clinical Pharmacology, EarlyView.
Aims Tranexamic acid (TXA) stabilizes clot formation by inhibiting fibrin degradation and improves postoperative outcomes. However, rare adverse events (e.g., thrombosis, seizures) warrant dose–risk evaluation. This study examines how perioperative blood loss and transfusion practices affect TXA concentrations during paediatric scoliosis surgery ...
Paula Alexandra Sá, Luisa Barreiros, Marcela A. Segundo, Eugénia Cruz, Sibylle Langenecker   +4 more
wiley   +1 more source

Direct Analysis of Living Objects by Extractive Electrospray Mass Ionization Spectrometry

CHIMIA, 2007
Huanwen Chen, Renato Zenobi
doaj   +1 more source

Lipidomic profiling of endometrial cancer using Desorption Electrospray Ionisation Mass Spectrometry Imaging

Paraskevaidi, Maria
openalex   +1 more source

Electrospray ionization with low-energy collisionally activated dissociation tandem mass spectrometry of glycerophospholipids: Mechanisms of fragmentation and structural characterization

, 2009
Fong‐Fu Hsu, John Turk
openalex   +1 more source

A Review on Quantitative Process Analytical Technology for Continuous Downstream Processing of Monoclonal Antibodies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The competition in the biopharmaceutical market is increasing due to the market entry of biosimilars and rising costs in research and development of new drugs. Hence, continuous manufacturing gained significant attention due to its potential in reducing production cycle times and costs, as well as the possibility of real‐time release testing ...
Mariana Carvalho, Ana Cruz, Cees Haringa, Marcel Ottens, Marieke Klijn   +4 more
wiley   +1 more source

Quantitative measurement of different ceramide species from crude cellular extracts by electrospray ionization tandem mass spectrometry (ESI-MS/MS)

, 1999
Gerhard Liebisch, Wolfgang Drobnik, Markus Reil, Barbara Trümbach, Ralf Arnecke, B. Olgemöller, A. Roscher, Gerd Schmitz   +7 more
openalex   +1 more source

Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

BMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang, Lu Han, He‐Qing Cai, Xin‐Yu Xue, Yi‐Fei Song, Wu‐Lin Xin, Ying‐Ze Wang, Peng Liu, Juan Liu   +8 more
wiley   +1 more source

DETERMINATION OF PESTICIDES IN WATER BY LIQUID CHROMATOGRAPHY-(ELECTROSPRAY IONIZATION)-MASS SPECTROMETRY (LC-ESI-MS)

, 2004
S. C. do N. de Queiroz, K. Lazou, Pat Sandra, Isabel Cristina Sales Fontes Jardim   +3 more
openalex   +2 more sources

Anti‐Inflammatory and Lipid Metabolism Modulatory Effects of Lantana camara L. Extract, With Enhanced Fibroblast Migration

Chemistry &Biodiversity, EarlyView.
This graphical abstract represents the main results of the study. It highlights the plant species under investigation: Lantana camara L. ABSTRACT Inflammation is a complex process associated with various chronic diseases. Lantana camara L., widely used in traditional medicine, exhibits diverse bioactivities, though its effects on lipid metabolism ...
Ari S. de O. Lemos, Matheus T. Branca, Lara M. Campos, Natasha S. Mayrink, Lívia R. Gamarano, João Pedro R. C. Bastos, Ana Julia de Almeida, Elaine S. Coimbra, Rodrigo L. Fabri   +8 more
wiley   +1 more source