Results 251 to 260 of about 776,948 (400)

Solvent Effects on the Conformation of the Transmembrane Peptide Gramicidin A: Insights from Electrospray Ionization Mass Spectrometry [PDF]

open access: bronze, 2000
Mario Bouchard   +4 more
openalex   +1 more source

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

open access: yesAdvanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu   +3 more
wiley   +1 more source

Real‐Time Eco–AI, Electrophoresis‐Correlative Data‐Dependent Acquisition with AI‐Based Data Processing Broadens Access to Single‐Cell Mass Spectrometry Proteomics

open access: yesAngewandte Chemie, EarlyView.
An affordable single‐cell proteomics workflow combines capillary electrophoresis, real‐time ion sorting, and AI‐aided spectral deconvolution to profile early Xenopus embryonic cells. Despite using a legacy Orbitrap, this strategy matches or exceeds the sensitivity of modern instruments, uncovering proteome dynamics at sub‐nanogram scale.
Bowen Shen, Fei Zhou, Peter Nemes
wiley   +2 more sources

Flexibility‐Aided Orientational Self‐Sorting and Transformations of Bioactive Homochiral Cuboctahedron Pd12L16

open access: yesAngewandte Chemie, EarlyView.
Mimicking concave morphologies found in nature, we have introduced flexible, unsymmetric, tridentate ligand (L) which undergoes coordination self‐assembly into highly organized chiral Pd6L8 or Pd12L16 cages that can undergo interspecific transformations. The cages, being based on natural amphiphilic transport molecules, mediate high cellular uptake and
Subhasis Chattopadhyay   +8 more
wiley   +2 more sources

Poly(ethyleneglycol) in electrospray ionization (ESI) mass spectrometry [PDF]

open access: bronze, 2000
S. Varray   +5 more
openalex   +1 more source

De Novo Designed β‐Hairpin Peptides Mimicking the Copper‐Binding Histidine Brace Motif of Lytic Polysaccharide Monooxygenases

open access: yesAngewandte Chemie, EarlyView.
In this work, the copper‐binding histidine brace (His‐brace) motif found in lytic polysaccharide monooxygenase (LPMO) enzymes was engineered in de novo designed peptides that fold as β‐hairpins (HisPins). Cu‐HisPins complexes showed LPMO‐like activity, including light‐stimulated melanin‐mediated oxidative cellulose degradation.
Enrico Falcone   +5 more
wiley   +2 more sources

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