Results 51 to 60 of about 39,518 (261)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Determination of the maximum mechanical stresses in the insulating material around a defect with a high dielectric permittivity in an electrostatic field

Electrical engineering & Electromechanics
Introduction. All insulating macrohomogeneous solid materials change shape under the influence of an electric field. Problem. The presence of minor defects changes the distribution of an electric field and causes a significant concentration of mechanical
O. О. Palchykov
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

DNA under Force: Mechanics, Electrostatics, and Hydration

Nanomaterials, 2015
Quantifying the basic intra- and inter-molecular forces of DNA has helped us to better understand and further predict the behavior of DNA. Single molecule technique elucidates the mechanics of DNA under applied external forces, sometimes under extreme ...
Jingqiang Li, Sithara S. Wijeratne, Xiangyun Qiu, Ching-Hwa Kiang   +3 more
doaj   +1 more source

Electrostatic powder attraction for the development of a novel recoating system for metal powder bed-based additive manufacturing

, 2022
Art. 103641, 9 S.The field of electrostatics and electrophotography offers great potential for applying powder layers for powder bed-based additive manufacturing processes, such as powder bed fusion of metals using a laser beam (PBF-LB/M).
Schilp, Johannes, Foerster, J., Schlick, Georg, Seidel, C., Frey, A., Michatz, M., Seidel, Christian, Schilp, J., Foerster, Julia, Binder, Maximilian, Schlick, G., Binder, M., Michatz, Marco, Frey, Alexander   +13 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Null-Result Test for Effect on Weight from Large Electrostatic Charge

Physics, 2021
We report test results searching for an effect of electrostatic charge on weight. For conducting test objects of mass of order 1 kg, we found no effect on weight, for potentials ranging from 10 V to 200 kV, corresponding to charge states ranging from 10 ...
George Hathaway, Lance L. Williams
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Effects of the electrostatic environment on the Majorana nanowire devices

New Journal of Physics, 2016
One of the promising platforms for creating Majorana bound states is a hybrid nanostructure consisting of a semiconducting nanowire covered by a superconductor. We analyze the previously disregarded role of electrostatic interaction in these devices. Our
A Vuik, D Eeltink, A R Akhmerov, M Wimmer   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source