Results 51 to 60 of about 35,013 (304)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A Predictive Model for Monolayer‐Selective Metal‐Mediated MoS2 Exfoliation Incorporating Electrostatics

Advanced Materials Interfaces
The metal‐mediated exfoliation (MME) method enables monolayer‐selective exfoliation of van der Waals (vdW) crystals, improving the efficacy of large monolayer production.
Alexander Corletto, Marco Fronzi, Alexis Krywula Joannidis, Peter C. Sherrell, Michael J. Ford, David A. Winkler, Joseph G. Shapter, James Bullock, Amanda V. Ellis   +8 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Physicochemical Rationale of Matrix Effects Involved in the Response of Hydrogel-Embedded Luminescent Metal Biosensors

Biosensors
There is currently a critical need for understanding how the response and activity of whole-cell bacterial reporters positioned in a complex biological or environmental matrix are impacted by the physicochemical properties of their micro-environment ...
Elise Rotureau, Christophe Pagnout, Jérôme F. L. Duval   +2 more
doaj   +1 more source

Proceedings of the 2016 Electrostatics Joint Conference

, 2022
As a charged object passes a grounded metal probe, a bipolar current signal is induced. By integrating the signal over time, the induced charge as a function of time can be obtained.
Matti Murtomaa, Jarno Salonen, Janne Peltonen   +2 more
core  

Preface [PDF]

, 2019
Electrostatics 2019 and Dielectrics 2019It is our pleasure and honour to introduce this prestigious publication – The Proceedings of the Institute of Physics International Conferences Electrostatics 2019 and Dielectrics 2019.
Hadjiloucas, S, Manivannan, N
core   +1 more source

Electrostatic powder attraction for the development of a novel recoating system for metal powder bed-based additive manufacturing

, 2022
Art. 103641, 9 S.The field of electrostatics and electrophotography offers great potential for applying powder layers for powder bed-based additive manufacturing processes, such as powder bed fusion of metals using a laser beam (PBF-LB/M).
Schilp, Johannes, Foerster, J., Schlick, Georg, Seidel, C., Frey, A., Michatz, M., Seidel, Christian, Schilp, J., Foerster, Julia, Binder, Maximilian, Schlick, G., Binder, M., Michatz, Marco, Frey, Alexander   +13 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Sustained intra-cartilage delivery of low dose dexamethasone using a cationic carrier for treatment of post traumatic osteoarthritis

European Cells & Materials, 2017
Disease-modifying osteoarthritis drugs (DMOADs) should reach their intra-tissue target sites at optimal doses for clinical efficacy. The dense, negatively charged matrix of cartilage poses a major hindrance to the transport of potential therapeutics.
AG Bajpayee, RE De la Vega, M Scheu, NH Varady, IA Yannatos, LA Brown, Y Krishnan, TJ Fitzsimons, P Bhattacharya, EH Frank, AJ Grodzinsky, RM Porter   +11 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source