Results 51 to 60 of about 26,359 (265)
Effects of the electrostatic environment on the Majorana nanowire devices
New Journal of Physics, 2016 One of the promising platforms for creating Majorana bound states is a hybrid nanostructure consisting of a semiconducting nanowire covered by a superconductor. We analyze the previously disregarded role of electrostatic interaction in these devices. Our
A Vuik +3 more
doaj +1 more source
Models of membrane electrostatics [PDF]
Physical Review E, 2012 I derive formulas for the electrostatic potential of a charge in or near a membrane modeled as one or more dielectric slabs lying between two semi-infinite dielectrics. One can use these formulas in Monte Carlo codes to compute the distribution of ions near cell membranes more accurately than by using Poisson-Boltzmann theory or its linearized version.
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Failure of Debye-Hückel Screening in Low-Charge Colloidal Suspensions
Colloids and Interfaces, 2018 Derjaguin–Landau–Verwey–Overbeek (DLVO) theory remains the cornerstone of colloid stability. Electrostatic interactions dominate van der Waals attractions at large colloid-colloid separations h, unless strongly screened.
Franceska Waggett +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Efficient Algorithms for Electrostatic Interactions Including Dielectric Contrasts
Entropy, 2013 Coarse-grained models of soft matter are usually combined with implicit solvent models that take the electrostatic polarizability into account via a dielectric background. In biophysical or nanoscale simulations that include water, this constant can vary
Christian Holm +5 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
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Education SciencesThe method of images (MoI) is a valuable technique for solving certain electrostatic boundary value problems consisting of charge density near conductor(s).
Jaya Shivangani Kashyap +2 more
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Modeling Electrostatic Force in Protein-Protein Recognition
Frontiers in Molecular Biosciences, 2019 Electrostatic interactions are important for understanding molecular interactions, since they are long-range interactions and can guide binding partners to their correct binding positions.
H. B. Mihiri Shashikala +2 more
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