Results 61 to 70 of about 35,013 (304)
DNA under Force: Mechanics, Electrostatics, and Hydration
Nanomaterials, 2015 Quantifying the basic intra- and inter-molecular forces of DNA has helped us to better understand and further predict the behavior of DNA. Single molecule technique elucidates the mechanics of DNA under applied external forces, sometimes under extreme ...
Jingqiang Li +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Electrical engineering & ElectromechanicsIntroduction. All insulating macrohomogeneous solid materials change shape under the influence of an electric field. Problem. The presence of minor defects changes the distribution of an electric field and causes a significant concentration of mechanical
O. О. Palchykov
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Null-Result Test for Effect on Weight from Large Electrostatic Charge
Physics, 2021 We report test results searching for an effect of electrostatic charge on weight. For conducting test objects of mass of order 1 kg, we found no effect on weight, for potentials ranging from 10 V to 200 kV, corresponding to charge states ranging from 10 ...
George Hathaway, Lance L. Williams
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Effects of the electrostatic environment on the Majorana nanowire devices
New Journal of Physics, 2016 One of the promising platforms for creating Majorana bound states is a hybrid nanostructure consisting of a semiconducting nanowire covered by a superconductor. We analyze the previously disregarded role of electrostatic interaction in these devices. Our
A Vuik +3 more
doaj +1 more source
A Simple Gas-Kinetic Model for Dilute and Weakly Charged Plasma Micro-Jet Flows
Fluids, 2021 This paper presents a simple model for slightly charged gas expanding into a vacuum from a planar exit. The number density, bulk velocity, temperature, and potential at the exit are given.
Shiying Cai, Chunpei Cai
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Small MethodsAbstract Electrification of ice has been studied for over half a century, mostly in the context of atmospheric science. Here, the polarizability and natural thermovoltage of a substrate‐bound frost sheet are exploited for frost removal by placing an actively charged electrode overhead.
Venkata Yashasvi Lolla +4 more
openaire +4 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source