Results 91 to 100 of about 4,761,213 (285)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Modeling fragmentation with new high order finite element technology and node splitting

EPJ Web of Conferences, 2015
The modeling of fragmentation has historically been linked to the weapons industry where the main goal is to optimize a bomb or to design effective blast shields.
Olovsson Lars, Limido Jérôme, Lacome Jean-Luc, Hanssen Arve Grønsund, Petit Jacques   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Short-range order in binary and multiple principal element alloys: A review

Matter and Radiation at Extremes
Multiple principal element alloys (MPEAs), also known as high-entropy alloys, have attracted significant attention because of their exceptional mechanical and thermal properties.
Yuxin Liu, Hongbo Lou, Fei Zhang, Zhidan Zeng, Qiaoshi Zeng   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Passive Synthesis of Immittance for Fractional-Order Three-Element-Kind Circuit

IEEE Access, 2019
As an interdisciplinary research area, fractional circuits and systems have attracted extensive attention of scholars and researchers for their superior performance and potential applications.
Guishu Liang, Jiawei Hao
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Wideband Vibro-Acoustic Coupling Investigation in Three Dimensions Using Order-Reduced Isogeometric Finite Element/Boundary Element Method

Journal of Marine Science and Engineering
This study introduces an innovative model-order reduction (MOR) technique that integrates boundary element and finite element methodologies, streamlining the analysis of wideband vibro-acoustic interactions within aquatic and aerial environments.
Yanming Xu, Xin Zhang, Jiachen Wang, Zhongming Hu   +3 more
doaj   +1 more source

Numerical solution for one-dimensional pure-convection problems using the high-order Taylor-Galerkin element-free method [PDF]

مهندسی عمران شریف
The present study proposes a novel approach for solving one-dimensional pure convection problems, utilizing a high-order Taylor Galerkin element-free method. The standard Galerkin method has limitations in solving such problems due to the predominance of
S. Espahbodi Nia, Ali Rahmani Firoozjaee
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source