Results 111 to 120 of about 4,727,754 (333)

Rational-approximation-based model order reduction of Helmholtz frequency response problems with adaptive finite element snapshots

, 2023
Francesca Bonizzoni, Davide Pradovera, Michele Ruggeri   +2 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A $C^0$ linear finite element method for sixth order elliptic equations [PDF]

, 2018
Hailong Guo, Zhimin Zhang, Qingsong Zou
openalex   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

An Arbitrary Order Virtual Element Method for Free Torsional Vibrations of Beams

Aerospace
In this study, a novel arbitrary order Virtual Element Method (p-VEM) for free torsional vibration analysis of beams with negligible warping is presented. This method can serve as an equivalent beam model for slender aerospace structural components.
Marco Lo Cascio, Alberto Milazzo
doaj   +1 more source

A Computational Study of Finite Element Methods for Second Order Linear Two-Point Boundary Value Problems [PDF]

, 1983
P. Keast, G. Fairweather, J. C. Diaz
openalex   +1 more source

Weak Galerkin finite element method for second order problems on curvilinear polytopal meshes with Lipschitz continuous edges or faces [PDF]

, 2023
Qingguang Guan, Gillian Queisser, Wenju Zhao   +2 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Design, synthesis and simulation of fractional-order element using MOS transistors as distributed resistive capacitive devices

Scientific Reports
The article presents a synthesis method to design electrical circuit elements with fractional-order impedance, referred to as a Fractional-Order Element (FOE) or Fractor, that can be implemented by Metal–Oxide–Semiconductor (MOS) transistors.
David Kubanek, Aleksandr Shadrin, Pavel Seda, Jan Dvorak, Jan Jerabek, Vilem Kledrowetz, Cole Christie, Todd J. Freeborn, Pyotr A. Ushakov   +8 more
doaj   +1 more source