Results 51 to 60 of about 106,299 (261)

3D Game-Based Learning Media Using a Deep Learning Approach to Enhance Understanding of Natural and Social Science (IPAS) Concepts

Jurnal Media dan Teknologi Pendidikan
The low level of students’ understanding of the IPAS concept, caused by insufficiently interactive learning and minimal use of digital media, forms the background of this study.
Ni Nengah Sari Jati, I Nyoman Laba Jayanta, I Made Hendra Sukmayasa   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The SAVI Learning Model Assisted by Manipulative Media Affects Students’ Mathematical Knowledge Competence

Indonesian Journal of Instruction
The lack of student involvement in the learning process and the lack of students' understanding of the subject matter of mathematics results in low knowledge competence in mathematics subjects.
Ni Komang Ayu Ariyanti Ariyanti, I Wayan Wiarta, Dewa Gede Firstia Wirabrata   +2 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Navigating Uncertainty: Exploring Elementary School Teachers' Perspectives on Metacognitive Development in the VUCA Era

Indonesian Journal on Learning and Advanced Education (IJOLAE)
Metacognition is the ability that learners have to know, control, and evaluate their thinking processes, as well as learning strategies, can be used to solve problems through three stages, namely the stages of understanding the problem, solving the ...
Widia Nur Jannah, Mubiar Agustin, Rahman Rahman, Tatang Herman   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Mathematical numeracy skills for pre-service teacher: An effectiveness of the STEAM framework

Social Sciences and Humanities Open
STEAM (Science, Technology, Engineering, Arts, and Mathematics) learning is an approach that integrates five disciplines. This approach positions mathematics not only as a stand-alone subject, but as an analytical foundation that supports numeracy skills
Malik Ibrahim, Heri Retnawati, Fery Muhamad Firdaus, Umar Umar, Mufidah Mufidah, Moh Rosyid Mahmudi, Theresa Dwita Haliem   +6 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Development of Digital Comic Media Based on Education for Sustainable Development (ESD) to Improve Cultural and Citizenship Literacy of Elementary Students

Jurnal Kependidikan
This research aims to develop digital comics media to increase students’ cultural and citizenship literacy based on Education for Sustainable Development (ESD).
Eka Putri Ramadhany, Mela Darmayanti, Kurniasih Kurniasih, Tatang Syaripudin   +3 more
doaj   +1 more source