Results 31 to 40 of about 8,218,490 (308)

The importance of elementary sexuality education [PDF]

, 2002
Plan BThe purpose of this paper is to look at the importance of elementary sexuality education in schools as well as look at its effect on children.
Meillier, Jill M.
core  

Sınıf Öğretmenlerinin Erken Cebire Yönelik Düşüncelerinin Belirlenmesi

, 2017
This study aimed to determine elementary teachers’ ideas about early algebra. Survey model was used in the study. The data was obtained through “Early Algebra Awareness Scale” developed by the researchers.
Özlem Doğan Temur, Doğan Temur, Özlem, Turgut, Sedat, Sedat Turgut   +3 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Montessori Yaklaşımın Çocukların Kavram Edinimi Üzerindeki Etkisinin İncelenmesi [PDF]

, 2014
: The main purpose of this research is to examine the effect of Montessori education approach on 4-6-year-old children’s concept acquisition such as school readiness, direction/position, self/social awareness, texture/material, quantity and time ...
Temel, Zeynep Fulya, TORAN, MEHMET
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

ARES (Augmented Reality-Ethnoscience): development of digital learning media to improve critical thinking ability in elementary school students

Primary: Jurnal Pendidikan Guru Sekolah Dasar
The 21st century presents various global challenges that require the development of students’ critical thinking skills; however, the lack of contextual digital media to support ecosystem observation has contributed to low levels of students’ critical ...
Zidni Alfian Barif, Apnorlince Paulus, Raihatul Jannah, Alwiana Hamidah Nugroho, Nabila Ariiqah   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Integrating The Traditional Game Gasing: Comparison and Correlation of Responses, Peace-Loving Character, Social Care, and Student Responsibility

Journal of Innovation in Educational and Cultural Research
The era of globalization and the rapid development of technology have made many children prefer online games over traditional games. This makes it difficult for children to socialize with the surrounding environment and have high individual character ...
Alirmansyah Alirmansyah, Muhammad Dewa Zulkhi, Pebri Azmi Pandya, Aqilla Fadia Haya, Vidia Wulandari   +4 more
doaj   +1 more source