Results 71 to 80 of about 107,693 (262)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Interactive Puzzle Based on Gamification Concepts Assisted by a Website on the Five Senses Material to Improve Learning Outcomes of Fourth-Grade Elementary School Students

Jurnal Media dan Teknologi Pendidikan
The low science learning outcomes of fourth-grade elementary school students on the five senses material are generally caused by the lack of variety and interactivity of the learning media used, so that students tend to be passive and easily bored. This
Anna Shau Tong, I Gede Margunayasa, I Wayan Widiana   +2 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Electronic Comic Media to Improve Elementary School Students’ Reading Interest and Reading Skills

Mimbar Ilmu
Reading interest and reading skills among elementary school students remain significant challenges in the learning process, particularly amid the rapid development of digital technology.
Ni Luh Putu Dian Astari, I Ketut Gading, Ni Ketut Desia Tristiantari   +2 more
doaj   +1 more source

Learning impacts on elementary education students during physical and social distancing due COVID-19. [PDF]

Codas, 2022
Barbosa ALA, Anjos ABLD, Azoni CAS.
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

The Effect of Drill Assisted CTL Model on the Mathematical Knowledge Competence of Fifth Grade Elementary School Students

Indonesian Journal of Instruction
Mathematics learning in elementary schools often faces the problem of students’ low conceptual understanding because the learning process tends to be procedural and is less connected to students’ real life contexts.
Dewa Ayu Shri Laksmi Prama Dewi, I Wayan Wiarta, Didith Pramunditya Ambara   +2 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Student Teams Achievement Division (STAD) Learning Model Assisted by Whole Number Puzzle Media to Enhance Mathematical Knowledge Competence

Mimbar Ilmu
Mathematics learning in elementary schools is often considered difficult and less engaging, particularly in the topic of whole numbers, which affects students’ knowledge competence.
Luh Ayu Trishna Savitri, Gusti Ngurah Sastra Agustika, Anak Agung Ayu Dewi Sutyaningsih   +2 more
doaj   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source