Results 81 to 90 of about 106,299 (261)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

The Effect of Drill Assisted CTL Model on the Mathematical Knowledge Competence of Fifth Grade Elementary School Students

Indonesian Journal of Instruction
Mathematics learning in elementary schools often faces the problem of students’ low conceptual understanding because the learning process tends to be procedural and is less connected to students’ real life contexts.
Dewa Ayu Shri Laksmi Prama Dewi, I Wayan Wiarta, Didith Pramunditya Ambara   +2 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Electronic Comic Media to Improve Elementary School Students’ Reading Interest and Reading Skills

Mimbar Ilmu
Reading interest and reading skills among elementary school students remain significant challenges in the learning process, particularly amid the rapid development of digital technology.
Ni Luh Putu Dian Astari, I Ketut Gading, Ni Ketut Desia Tristiantari   +2 more
doaj   +1 more source

Learning impacts on elementary education students during physical and social distancing due COVID-19. [PDF]

Codas, 2022
Barbosa ALA, Anjos ABLD, Azoni CAS.
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Interactive Puzzle Based on Gamification Concepts Assisted by a Website on the Five Senses Material to Improve Learning Outcomes of Fourth-Grade Elementary School Students

Jurnal Media dan Teknologi Pendidikan
The low science learning outcomes of fourth-grade elementary school students on the five senses material are generally caused by the lack of variety and interactivity of the learning media used, so that students tend to be passive and easily bored. This
Anna Shau Tong, I Gede Margunayasa, I Wayan Widiana   +2 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Student Teams Achievement Division (STAD) Learning Model Assisted by Whole Number Puzzle Media to Enhance Mathematical Knowledge Competence

Mimbar Ilmu
Mathematics learning in elementary schools is often considered difficult and less engaging, particularly in the topic of whole numbers, which affects students’ knowledge competence.
Luh Ayu Trishna Savitri, Gusti Ngurah Sastra Agustika, Anak Agung Ayu Dewi Sutyaningsih   +2 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source