Results 41 to 50 of about 272,865 (318)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Determination of fission fragment yields using the sorbtion process [PDF]

Ядерна фізика та енергетика, 2007
The separation of iodine isotopes from the sum of 235U fission products by the sorption process from water solution using coal sorbent SKS was investigated. The sorption coefficient values in range 0,7 - 0,9 was obtained.
H. V. Vasylyeva, V. S. Kouts, V. A. Pylypchenko, A. P. Osypenko   +3 more
doaj  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Bit from Qubit. A Hypothesis on Wave-Particle Dualism and Fundamental Interactions

Information, 2020
In this article a completely objective decoherence mechanism is hypothesized, operating at the level of the elementary particles of matter. The standard quantum mechanical description is complemented with a phenomenological evolution equation, involving ...
Leonardo Chiatti
doaj   +1 more source

АКТУАЛЬНЫЕ ВОПРОСЫ ИСПОЛЬЗОВАНИЯ ИНФОРМАЦИОННЫХ ТЕХНОЛОГИЙ В ОБУЧЕНИИ ФИЗИКО-МАТЕМАТИЧЕСКИМ ДИСЦИПЛИНАМ

Научно-педагогическое обозрение, 2022
В современном обществе меняются способы получения образования с акцентом на усиление роли интернет-сетей как источника информации. Помимо этого, набирают силу диалоговые методы обучения.
Азоркина Олеся Демидовна, Кириллова Елена Николаевна   +1 more
doaj   +1 more source

The Search for Stable, Massive, Elementary Particles

, 2001
In this paper we review the experimental and observational searches for stable, massive, elementary particles other than the electron and proton. The particles may be neutral, may have unit charge or may have fractional charge.
Abe F., Acciarri M., Akers R., Barish B., Barwick S. W., Baudis L., Caso C., Davidson S., Davidson S., Derbin A. V., Dick W. J., Dimopoulos S., DINESH LOOMBA, Ellis J., ERIC R. LEE, Ficenec D. J., Golowich E., Goodman M. W., Green A. M., Hemmick T. K., IRWIN T. LEE, Jones W. G., KLAUS S. LACKNER, Lackner K. S., Mar N. M., MARTIN L. PERL, Millikan R. A., Mohapatra R. N., Mori M., PETER C. KIM, Starkman G. D., Turkevich A., VALERIE HALYO, Yamagata T.   +33 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

A Eterna Busca do Indivisível: do Átomo Filosófico aos Quarks e Léptons The eternal search for the indivisible: from philosophical atom to quarks and leptons

Química Nova, 1997
The fascinating search of the inner boundaries of the Universe, has been entangled, since the birth of greek philosophy 25 centuries ago, with the main epistemological changes in the History of Science.
Francisco Caruso, Vitor Oguri
doaj   +1 more source

Penning traps as a versatile tool for precise experiments in fundamental physics

, 2009
This review article describes the trapping of charged particles. The main principles of electromagnetic confinement of various species from elementary particles to heavy atoms are briefly described.
Altarelli G., Blaum K., Blaum K., Block M., Boehm C., Bollen G., Frekers D., G. Werth, Ghosh P. K., Itzykson C., K. Blaum, Major F. G., Van Dyck R. S., Yu. N. Novikov   +13 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source