Results 41 to 50 of about 223,481 (318)
MEMBENTUK AKHLAK DI ERA REVOLUSI INDUSTRI 4.0 DENGAN PERAN PENDIDIKAN AGAMA ISLAM
Elementary School, 2021 Advances in science and technology entering the millennial era of industrial revolution 4.0 can be enjoyed by mankind. But onthe other hand, the advancement of science and technology also has a negative impact on many people, especially in today's ...
Arip Febrianto, Norma Dewi Shalikhah
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
PENGEMBANGAN BAHAN AJAR MULTIMEDIA UNTUK PEMBELAJARAN IPA SD
Elementary School, 2020 Based on preliminary study, it was found the problem that teachers often had difficulty to give real picture related to materials which are beyond the observation of students. The limitations of media and learning resources forced teachers to deliver the
Dhian Dwi Nur Wenda
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Elementary School, 2021 The objectives of this study are : (1) to analyze the real condition of students’achievements in SD Muhammadiyah Wirobrajan II in implementing Iqro method,(2) To analyze the real condition of students’ achievements in SD Muhammadiyah Wirobrajan II in ...
Sri Agustinawati +3 more
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Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Elementary School, 2020 This paper is aimed to create a learning media in the form of a module as a source of mathematics learning based on contextual approach to PGSD student in order to facilitate them to understand the concept and the student independence learning in terms ...
Danuri .
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Elementary School, 2020 The purpose of this research is to improve the students' active participation and citizenship skills (civic skills) students learning civics in elementary schools using the model of Portfolio Based Learning.
Widya Trio Pangestu , Prima Rias Wana
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source