Results 51 to 60 of about 8,635,557 (306)

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

PENGARUH MODEL PEMBELAJARAN PROJECT BASED LEARNING TERHADAP HASIL BELAJAR SISWA KELAS V SD SAWAH BESAR 01

open access: yesElementary School, 2020
This research aims to examine the effect of project-based learning through biopore learning models on the learning outcomes of elementary school students in grade V, to examine the effect of project-based learning through biopori learning outcomes on ...
Didi Prabowo   +2 more
doaj   +1 more source

MEMBENTUK AKHLAK DI ERA REVOLUSI INDUSTRI 4.0 DENGAN PERAN PENDIDIKAN AGAMA ISLAM

open access: yesElementary School, 2021
Advances in science and technology entering the millennial era of industrial revolution 4.0 can be enjoyed by mankind. But onthe other hand,  the advancement of science and technology also has a negative impact on many people, especially in today's ...
Arip Febrianto, Norma Dewi Shalikhah
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Polk Elementary School, 1993

open access: yes, 1992
Polk Elementary School was founded in 1960 as an African-American School for the East Baton Rouge Parish School System. In 1989, Polk elementary was integrated.
Polk Elementary School
core   +1 more source

PENGEMBANGAN BAHAN AJAR MULTIMEDIA UNTUK PEMBELAJARAN IPA SD

open access: yesElementary School, 2020
Based on preliminary study, it was found the problem that teachers often had difficulty to give real picture related to materials which are beyond the observation of students. The limitations of media and learning resources forced teachers to deliver the
Dhian Dwi Nur Wenda
doaj   +1 more source

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