Results 61 to 70 of about 647,579 (345)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

The impact of reduced time spent outdoors during the Covid-19 lockdown on the health and well-being of young people in Czechia

open access: yesActa Universitatis Carolinae Geographica, 2022
It was not officially possible to leave the cadastral territory for recreational purposes in Czechia during the period from the 1 March to the 21 March 2021. The aim of this study was to evaluate how this lockdown affected the amount of time young people
Dominik Rubáš   +2 more
doaj   +1 more source

Building Tolerance Among Elementary School Students in Multicultural Education from Elementary School to College

open access: yesMimbar Sekolah Dasar
The level of tolerance and appreciation for cultural diversity among elementary and university students remains relatively low. This research is considered urgent because of the discrepancy between societal expectations and the realities observed in educational settings, where tolerance as a foundation for fostering inclusive and harmonious attitudes ...
Rajaloa, Nani I.   +2 more
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Asesmen Cepat Kerentanan Bangunan Sekolah Muhammadiyah Terhadap Gempabumi di Kecamatan Kasihan Bantul DIY

open access: yesSemesta Teknika, 2017
School buildings are included as buildings with risk category IV (SNI 1726: 2012) because it is potentially causing multiple casualties if earthquakes occur during school hours.
Restu Faizah, Muhammad Ibnu Syamsi
doaj  

The Kind of Transportation Used Between Home and School in Children and Perception of Urban Space: Case of Kirklareli

open access: yesProceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA, 2020
The type of transportation used has an impact on the perception of urban space. For children, traveling by foot or cycling is an action beyond reaching a place.
Merve GÜROĞLU AĞDAŞ
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

A survey of administrative and teacher attitude toward the lengthening of the school day [PDF]

open access: yes, 1956
Thesis (M.A.)--Boston ...
Caswell, George E   +1 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Idle-Free Campaign Survey Results and Idling Reductions in an Elementary School

open access: yesVehicles, 2022
Air pollution near schools is particularly problematic. Pollution emissions from vehicle idling at or around schools may have significant effects on children’s health including increased rates of asthma and childhood leukemia. Outdoor pollution emissions
Daniel L. Mendoza   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy