FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Positive selection on brain cis-regulatory elements in the human lineage drives changes in gene expression and susceptibility to neuropsychiatric disorders. [PDF]
HGG AdvTouissi Y, Vallender EJ.
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Practical applications of gamification in patient-centered outcomes research and digital health, and its acceptance in clinical trials. [PDF]
Front Digit HealthHartford C +5 more
europepmc +1 more source
Anthropic Activity Markers 2.0: A Shift Towards Compositional Data Analysis. [PDF]
J Archaeol Method TheoryRuiz-Giralt A +7 more
europepmc +1 more source
Prediction of Nuclear Magnetic Resonance Surface Relaxivity for Shales. [PDF]
ACS OmegaCheng J, Zhang S, Song X.
europepmc +1 more source
Design and Validation of a Minimum Dataset for a Self-Care Mobile Application for Patients With Diabetic Retinopathy: Descriptive-Validation Study. [PDF]
Health Sci RepPaghe A +3 more
europepmc +1 more source
Longitudinal Repeatome Remodeling in Peripheral Blood Following Parkinson's Disease Diagnosis. [PDF]
Genes (Basel)Kulski JK, Koks S.
europepmc +1 more source