Results 231 to 240 of about 10,280,410 (290)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Multiple-element exposure in early pregnancy and birth defects: a nested case-control study based on the China birth cohort study. [PDF]

open access: yesFront Nutr
Zhang W   +11 more
europepmc   +1 more source

Safety of Commercial Cod Products and Potential Impact on Consumers. [PDF]

open access: yesFoods
Nava V   +5 more
europepmc   +1 more source

Transposable elements

Current Biology, 1992
Transposable elements comprise a major fraction of eukaryotic genomes. They are studied both because of their intrinsic biological interest and because they can be exploited as valuable research tools. Many interesting papers dealing with various aspects of the biology of these elements have been published during the past year and a number of new ...
openaire   +2 more sources

Transposable Elements

2019
Transposable elements (TEs) are low-complexity elements (e.g., LINEs, SINEs, SVAs, and HERVs) that make up to two-thirds of the human genome. There is mounting evidence that TEs play an essential role in molecular functions that influence genomic plasticity and gene expression regulation.
G, Guffanti   +4 more
openaire   +2 more sources

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