Results 51 to 60 of about 8,225,009 (301)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk   +10 more
wiley   +1 more source

System Elements Identification Method for Heat Transfer Modelling in MBSE

open access: yesSystems
Today’s systems are becoming increasingly complex due to the multitude of interactions between subsystems. This is also true for the electromechanical drivetrain and its physically interacting cooling system.
Patrick Jagla   +6 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin   +17 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann   +8 more
wiley   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari   +5 more
wiley   +1 more source

Novel Thermal Wear Simulation Approach to Model Transient Wear and Friction in Sliding Bearings

open access: yesLubricants
Wear occurs in sliding bearings as they often operate under mixed friction conditions in heavy-duty applications. Over the years, this has led to the development of wear simulations to predict wear evolution in sliding bearings. As part of wear evolution,
Anuj Khare   +6 more
doaj   +1 more source

On the stiffness of surfaces with non-Gaussian height distribution

open access: yesScientific Reports, 2021
In this work, the stiffness, i.e., the derivative of the load-separation curve, is studied for self-affine fractal surfaces with non-Gaussian height distribution. In particular, the heights of the surfaces are assumed to follow a Weibull distribution. We
Francesc Pérez-Ràfols   +1 more
doaj   +1 more source

Cognitive Elements of Empowerment: An “Interpretive” Model of Intrinsic Task Motivation

open access: yes, 1990
This article presents a cognitive model of empowerment. Here, empowerment is defined as increased intrinsic task motivation, and our subsequent model identifies four cognitions (task assessments) as the basis for worker empowerment: sense of impact ...
K. Thomas, B. Velthouse
semanticscholar   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad   +9 more
wiley   +1 more source

Development of a machine learning-based surrogate model for friction prediction in textured journal bearings

open access: yesFriction
Surface textures in journal bearings offer significant potential for reducing friction and enhancing energy efficiency. However, the complexity of texture configurations necessitates an accurate and efficient performance prediction model to properly ...
Yujun Wang   +4 more
doaj   +1 more source

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