Results 131 to 140 of about 410,054 (317)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Elevated [CO2] alleviates AsGH3.8-mediated stolon growth inhibition via IAA accumulation and soluble sugar reduction in perennial grass

Environmental and Experimental Botany
Rapid stolon growth is advantageous for greater turf density and faster establishment. Elevated CO2 concentration ([CO2]) can stimulate stolon growth by increasing the levels of auxin indole-3-acetic acid (IAA) in stolon nodes and internodes of ...
Tian Hao, Ruonan Li, Ruying Wang, Xiujiang Yan, Qiuguo Li, Ningli Fan, Zhimin Yang, Jingjin Yu   +7 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Nitrogen deposition limits photosynthetic response to elevated CO2 differentially in a dioecious species

, 2011
Sexual dimorphisms of dioecious plants are important in controlling and maintaining sex ratios under changing climate environments. Yet, little is known about sex-specific responses to elevated CO2 with soil nitrogen (N) deposition.
Xu, Xiao, Korpelainen, Helena, Li, CY (reprint author), Chinese Acad Sci, Chengdu Inst Biol, POB 416, Chengdu 610041, Peoples R China., Zhang, Yuanbin, Li, Chunyang, Zhao, Hongxia   +5 more
core  

Leaf photosynthesis and yield components of mung bean under fully open-air elevated [CO2]

, 2015
Mung bean (Vigna radiata L.) has the potential to establish symbiosis with rhizobia, and symbiotic association of soil micro flora may facilitate the photosynthesis and plant growth response to elevated [CO2].
Seneweera, Saman, Zong, Yu-zheng, Qi DONG, Xing-yu HAO, Li, Ping, Dong, Qi, Ji GAO, Saman Seneweera, Er-da LIN, Lin, Er-da, Xue HAN, Ping LI, Hao, Xing-yu, Gao, Ji, Yu-zheng ZONG, Han, Xue   +15 more
core   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Sex-specific responses of Populus yunnanensis exposed to elevated CO2 and salinity

, 2013
Populus yunnanensis Dode., a native dioecious woody plant in southwestern China, was employed as a model species to study sex-specific morphological, physiological and biochemical responses to elevated CO2 and salinity.
Luo, Jianxun, Li, Ling, Korpelainen, Helena, Li, CY (reprint author), Chinese Acad Sci, Chengdu Inst Biol, POB 416, Chengdu 610041, Peoples R China., Zhang, Yuanbin, Li, Chunyang   +5 more
core  

Increased capacity for photosynthesis in wheat grown at elevated CO2 : the relationship between electron transport and carbon metabolism

, 1995
Spring wheat (Triticum aestivum L.) was grown under optimal nutrition for six weeks at 700 and 350 μmol·mol-1 CO2 and simultaneous measurements of photosystem-II (PSII) chlorophyll fluorescence and gas exchange were conducted on intact attached leaves ...
Paul, Matthew J., Paul, M. J., Parry, M. A. J., Keys, Alfred J., Habash, Dimah Z., Parry, Martin A J, Habash, D. Z., Lawlor, David W., Keys, A. J., Lawlor, D. W.   +9 more
core   +1 more source

Effects of shading in different developmental phases on biomass and grain yield of winter wheat at ambient and elevated CO2

, 1996
Winter wheat (Triticum aestivum cv, Mercia) was grown in a controlled-environment facility under simulated field conditions at ambient (360 mu mol mol(-1)) and elevated (690 mu mol mol(-1)) CO2 concentrations, Some of the plants were shaded to mimic ...
Gibbard, C. L., Mitchell, V. J., Mitchell, R. A. C., Lawlor, D. W.   +3 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source