Results 41 to 50 of about 1,758,589 (312)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Residual Properties of Fibre Grids Embedded in Cementitious Matrices after Exposure to Elevated Temperatures

Buildings, 2023
The use of fabrics in the form of grids embedded in cementitious matrices—usually termed as textile-reinforced mortar, fiber-reinforced cementitious matrix, or textile-reinforced concrete—demonstrate a more stable performance in elevated temperature ...
Pengliang Yang, Theofanis Krevaikas
doaj   +1 more source

Elevated-temperature impact toughness of Mg–(Gd, Y)–Zr alloy [PDF]

, 2013
The Charpy impact results for Mg–10Gd–3Y–0.5Zr and Mg–11Y–5Gd–2Zn–0.5Zr alloys at various temperatures showed that Mg–10Gd–3Y–0.5Zr was more sensitive to temperature. The increase in impact toughness with temperature was related to the blunt crack-tip at
Anyanwu, Anyanwu, D.D. Yin, He, Hu, Hu, Janik, Kum, Liao, Liao, Liu, M.L. Hu, Ma, Q.D. Wang, Somekawa, Somekawa, Somekawa, Somekawa, Somekawa, Somekawa, Somekawa, V. Janik, Y.L. Mu, Yin, Yin   +24 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Integrative morpho-physiological and transcriptomic insights into wheat responses to combined drought, heat, and elevated CO₂ under future climate conditions

Plant Stress
Climate change intensifies environmental stressors such as drought and heat, posing a significant threat to crop productivity, while elevated CO2 concentrations generally have a positive effect on photosynthetic performance and, under certain conditions,
Zbyněk Milec, Kashif Nawaz, Swati Puranik, Anna Nowicka, Martin Kovačik, Hana Findurová, Emmanuel Opoku, Ales Pecinka, Karel Klem, Otmar Urban, Pranav Pankaj Sahu   +10 more
doaj   +1 more source

Inelastic Material Models of Type 316H for Elevated Temperature Design of Advanced High Temperature Reactors

Energies, 2020
In this paper, the inelastic material models for Type 316H stainless steel, which is one of the principal candidate materials for elevated temperature design of the advanced high temperature reactors (HTRs) pressure retained components, are investigated ...
Gyeong-Hoi Koo, Ji-Hyun Yoon
doaj   +1 more source

Durability characteristics of millet hush ash: A study on self-compacting concrete

Teknika, 2021
Judul: Karakteristik daya tahan abu sekam milet: Studi tentang beton SCC (self-compacting concrete) Title: Durability characteristics of millet hush ash: A study on self-compacting concreteDaya tahan adalah salah satu perhatian utama dalam industri beton.
Abubakar Mohammed, Aaron Aboshio
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Effect of Elevated Temperature on the Behavior of Amorphous Metallic Fibre-Reinforced Cement and Geopolymer Composites

Fibers, 2023
To improve the tensile, flexural, and ductility properties of geopolymer composites, amorphous metallic fibres (AMF) are used to reinforce these composites, and the behavior of these composites at elevated temperatures has been assessed in this study ...
Faiz Uddin Ahmed Shaikh, Narwinder Singh Kahlon, Attiq Ur Rahman Dogar   +2 more
doaj   +1 more source