Results 81 to 90 of about 1,191,943 (292)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Metacommunity Structures of Macroinvertebrates and Diatoms in High Mountain Streams, Yunnan, China

Frontiers in Ecology and Evolution, 2020
The metacommunity concept has received increasing interest in the past two decades. However, there has been limited research examining metacommunity structure of communities in high mountain streams.
Angelika L. Kurthen, Angelika L. Kurthen, Angelika L. Kurthen, Fengzhi He, Fengzhi He, Fengzhi He, Xiaoyu Dong, Alain Maasri, Alain Maasri, Naicheng Wu, Qinghua Cai, Sonja C. Jähnig, Sonja C. Jähnig   +12 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The second Euro Heart Survey on acute coronary syndromes: characteristics, treatment, and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004 [PDF]

, 2006
Aims Our study aimed to examine the management of acute coronary syndromes (ACS) in Europe and the Mediterranean basin, and to compare adherence to guidelines with that reported in the first Euro Heart Survey on ACS (EHS-ACS-I), 4 years earlier ...
Takács, János, Boyko, Valentina, Mandelzweig, Lori, Werf, Frans, Van de, Kovács, Aranka, Danchin, Nicolas, Filippatos, Gerasimos, Bodonovits, István, Gitt, Anselm, Wallentin, Lars, Hasin, Yonathan, Hasdai, David, Behar, Shlomo, Kovács Szentes, Ferenc, Marrugat, Jaume, Csoti, Éva, Bueno, Hector, Préda, István, Battler, Alex   +18 more
core   +1 more source

Room temperature in scientific protocols and experiments should be defined: a reproducibility issue

BioTechniques, 2021
Jaime A Teixeira da Silva
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI) [PDF]

, 2014
AimDespite prompt revascularization of acute myocardial infarction (AMI), substantial myocardial injury may occur, in part a consequence of ischaemia reperfusion injury (IRI). There has been considerable interest in therapies that may reduce IRI.
Singh, Satnam, Lim, Pitt O, Christopher Neil (433186), Bruce, M, Broadhurst, Paul, Madhani, Melanie; id_orcid, Nishat Siddiqi (7733786), Schwarz, Konstantin, Awsan, Noman, Jansen, Else, McPherson, Gladys, Dawson, Dana, Slattery, Elaine, Struthers, Allan, McDonald, Alison, Rhodes, Jonathan, Neil, Christopher, Toff, William, Bruce, M., Garg, Deepak, Siddiqi, N, Firoozi, Sami, Kaski, JC, Madhani, M., Nicholas Boon (7733804), Kaski, Juan-Carlo, Sofia Papadopoulou (7733789), Horowitz, J, Bennett, Lorraine, Horowitz, J., Frenneaux, Michael, Boon, N., Bruce, Margaret, Hildick-Smith, David, Lim, P., Neil, C., Nightingale, Peter, Pitt O. Lim (7733795), Graeme MacLennan (275485), Hannah, Andrew, Feelisch, M., Melanie Madhani (3851305), Roberts, Elved, Dawson, D, David Hildick-Smith (7733798), Madhani, M, Kaski, Juan Carlos, Lim, PO, Stewart, Andrew, Cooter, Nina, Rajendran, Sharmalar, Horowitz, John, Lang, Chim, Papadopoulou, Sofia A., NIAMI investigators, Jagpal, Baljit, Cotton, S, Siddiqi, N., Gonzalvez, Fatima, Feelisch, Martin, Madhani, Melanie, Boon, Nicholas, Nicholas Bunce (7733792), Brown, Sue, Roy, David, Bunce, N., Bunce, N, Papadopoulou, S, Dawson, D., Frenneaux, M., Michael Frenneaux (3576296), Davidson, Tracey, Siddiqi, Nishat, Dargie, Henry, Feelisch, M, Neil, C, Dana Dawson (7020656), Hildick-Smith, D., Frenneaux, M, Hildick-Smith, D, Bunce, Nicholas, NIAMI investigators (7733810), Cotton, Seonaidh, Seonaidh Cotton (503485), de Belder, Adam, Papadopoulou, S., Black, Marilyn, Kaski, J., Hogg, Duncan, Dautov, Rustem, Metcalfe, Malcolm, Bogle, Richard, Cotton, S., Boon, N, Martin Feelisch (358503), John Horowitz (7733801), Margaret Bruce (782483), Lim, Pitt O., MacLennan, G, Cotton, Seonaidh Claire, Juan Carlos Kaski (7733807), Maclennan, Graeme, Papadopoulou, Sofia, MacLennan, G.   +103 more
core   +1 more source

Komunitas Burung pada Pegunungan Bawah dan Sub-Pegunungan Di Taman Nasional Gunung Halimun Salak

Journal of Natural Resources and Environmental Management, 2019
Bird diversity has been known to be affected by various factors, including elevational gradient. The objective of this study was to describe the bird community trend and its associated habitat conditions on lower mountain and sub-mountain areas.
Kanthi Hardina, Yeni Aryati Mulyani, Ani Mardiastuti   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source