Results 81 to 90 of about 10,045 (263)

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Elevation zones Hallstätter Gletscher, Dachstein, Austria, 2017/2018

, 2019
Elevation zones Hallstätter Gletscher, Dachstein, Austria, 2017 ...
Reingruber, Klaus, Klaus Reingruber (6957842), Hartl, Lea, Stocker-Waldhuber, Martin, Fischer, Andrea, Andrea Fischer (6957836), Martin Stocker-Waldhuber (6957839), Helfricht, Kay, Lea Hartl (6965732), Kay Helfricht (7884212)   +9 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

The Effects Of Tides And Waves On Water-Table Elevations In Coastal Zones

Hydrogeology Journal, 1996
A resurgence of interest in the literature about coastal zones has highlighted the fact that ocean processes can have a significant influence on unconfined coastal aquifers, resulting in a net super-elevation of the water table at the land-ocean boundary to groundwater discharge.
Turner, Ian, Coates, B, Acworth, Richard
openaire   +1 more source

Elevation zones Mullwitzkees, Hohe Tauern, Austria, 2007/2008

, 2013
Elevation zones Mullwitzkees, Hohe Tauern, Austria, 2007 ...
Kuhn, Michael, Michael Kuhn (6957845), Stocker-Waldhuber, Martin, Fischer, Andrea, Andrea Fischer (6957836), Martin Stocker-Waldhuber (6957839)   +5 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Climate and soil factors co-derive the functional traits variations in naturalized downy thorn apple (Datura innoxia Mill.) along the altitudinal gradient in the semi-arid environment

Heliyon
Plant functional traits are consistently linked with certain ecological factors (i.e., abiotic and biotic), determining which components of a plant species pool are assembled into local communities.
Nasrullah Khan, Rafi Ullah, Mohammad K. Okla, Mostafa A. Abdel-Maksoud, Ibrahim A. Saleh, Hashem A. Abu-Harirah, Tareq Nayef AlRamadneh, Hamada AbdElgawad   +7 more
doaj   +1 more source

Elevation zones Venedigerkees, Hohe Tauern, Austria, 2012/2013

, 2014
Elevation zones Venedigerkees, Hohe Tauern, Austria, 2012 ...
Seiser, Bernd, Fischer, Andrea, Andrea Fischer (6957836), Bernd Seiser (6957848)   +3 more
core   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Projected rising temperatures and vapour pressure deficit threaten Arabica coffee production Tanzania's burgeoning coffee region: Empirical insight from Mbinga district, Tanzania

Environmental Challenges
Tanzania is emerging as a key coffee producer, but climate change poses a serious threat to coffee production in the country. While extensive literature addresses climatic variables’ trends and variability in coffee-growing regions globally, elevation, a
Ng'winamila Kasongi, Nestory Yamungu, Caleb Gallemore, Kristjan Jespersen   +3 more
doaj   +1 more source