Results 61 to 70 of about 10,045 (263)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Elevation zones Jamtalferner, Silvretta, Austria, 2017/2018

open access: yes, 2019
Elevation zones Jamtalferner, Silvretta, Austria, 2017 ...
Janicke, Andrina   +3 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Remote sensing and GIS-based forest fire risk zone mapping: The case of Manisa, Turkey

open access: yesTurkish Journal of Forestry, 2020
The aim of this research is to map the potential forest fire risk zones using various landscape analysis techniques in Manisa province, Turkey. Forest fire, which is defined as an ecological disaster caused by natural processes or as a result of human ...
Derya GÜLÇİN, Bülent DENİZ
doaj   +1 more source

Elevation zones Jamtalferner, Silvretta, Austria, 2009/2010

open access: yes, 2013
Elevation zones Jamtalferner, Silvretta, Austria, 2009 ...
Markl, Gerhard   +5 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Elevation zones Jamtalferner, Silvretta, Austria, 1988/1989

open access: yes, 2013
Elevation zones Jamtalferner, Silvretta, Austria, 1988 ...
Markl, Gerhard   +3 more
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Ecological drivers of tree diversity and distribution along an elevation zone in Mamley watershed of Sikkim, India

open access: yesGeology, Ecology, and Landscapes
Tree species diversity plays a crucial role in forest structure. This study assessed the species diversity, floristic composition, and vegetation structure along three elevation zones (lower elevation (LE) (2100 m)) and identified the ecological drivers ...
Mamta Chettri   +5 more
doaj   +1 more source

Elevation zones Jamtalferner, Silvretta, Austria, 1990/1991

open access: yes, 2013
Elevation zones Jamtalferner, Silvretta, Austria, 1990 ...
Markl, Gerhard   +3 more
core   +1 more source

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