Results 121 to 130 of about 201,568 (300)

Elevating form and elevating modulation

Popular Music, 2014
AbstractThe device known as, among other terms, truck-driver modulation, arranger's modulation and pump-up modulation is an important procedure for popular music, and one that merits a place in the harmony textbook. Emerging from a discussion of nomenclature, this paper proposes the terms of its title, which distinguishes between modulation as part of ...
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Research on Distributed Fault Diagnosis Model of Elevator Based on PCA-LSTM

Algorithms
A Distributed Elevator Fault Diagnosis System (DEFDS) is developed to tackle frequent malfunctions stemming from the widespread distribution and aging of elevator systems.
Chengming Chen, Xuejun Ren, Guoqing Cheng   +2 more
doaj   +1 more source

Spin tests of a single-engine, high-wing light airplane [PDF]

The airplane has a relatively steep spin mode (low angle of attack) with a high load factor and high velocity. The airplane recovers almost immediately after any deviation from the prospin control positions, except for one maneuver with reduced ...
Brown, P. W., Moul, T. M., Stewart, E. C., Suit, W. T.   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Assessing Comfort and Safety in Use of Elevators’ Human–Machine Interaction Devices

Buildings
Elevators are essential for accessibility and play a key role in a building’s functionality. Normally mass-produced and purchased from catalogs, elevators require thoughtful integration into architectural design to meet ergonomic, aesthetic, and safety ...
Giovanni Perrucci, Marco Costa, Elena Giacomello, Dario Trabucco   +3 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The numerical simulation study of traction elevator steel belt model

Mechanics & Industry
Due to the advantages of high comfort, low power consumption, and energy conservation and environmental protection, traction belt elevators are being increasingly utilized in various scenarios, and the performance of the steel belt under extreme ...
Li Chen, Hu Yuchao, Zhang Cai, Xu Feng, Zhou Zecheng, Wang Qinye   +5 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source