Results 111 to 120 of about 201,568 (300)

A passive gust alleviation system for a light aircraft [PDF]

open access: yes
A passive aeromechanical gust alleviation system was examined for application to a Cessna 172. The system employs small auxiliary wings to sense changes in angle of attack and to drive the wing flaps to compensate the resulting incremental lift.
Harlan, R. B., Roesch, P.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Measurements of Rudder Moments on an Airplane During Flight [PDF]

open access: yes
Tests indicated that: 1) C airplanes with two struts are extremely susceptible to aileron maneuvers, slight alterations of the aileron sufficing to compensate great unequalized moments; 2) great unequalized moments can be produced or neutralized by the ...
Heidelberg, Ing V
core   +1 more source

Vol. 2 (pp. 677-1996). “Library notes” by researcher: summaries and long excerpts of testimony by workers about Margaret Schwartz’s death in the fire; engineers, laborers, and hardware dealer about condition of door casing, handrail, lock; and co-defendant/owner Max Blanck about his actions on day of fire [PDF]

open access: yes, 1911
Vol. 2 (pp. 677-1996) “Library Notes,” picks up at page 677, continues to p. 1996 (61-page document), includes excerpts from transcript, more testimony from workers about the fire, what happened to Margaret Schwartz; testimony by engineer as to condition

core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Why Don't Country Elevators Pay Less for Low Quality Wheat? Information, Producer Preferences and Prospect Theory [PDF]

open access: yes
Previous research found that country elevators that are the first in their area to grade wheat and pay quality-adjusted prices would receive above-normal profits at the expense of their competitors.
Adam, Brian D., Hong, Seung Jee
core   +1 more source

Apparatus for sequentially transporting containers [PDF]

open access: yes, 1982
Apparatus for transferring and manipulating a plurality of containers in a sequence is disclosed including a mechanical manipulator arm having a gripping device which automatically picks up a container at a fixed pickup position P and transfers it to a ...
Hudgins, J. L.
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Elevator Control Simulation Using Fuzzy Logic Management

open access: yesJuTISI (Jurnal Teknik Informatika dan Sistem Informasi)
The use of a permanent magnet synchronous motor as an actuator in a ropeless elevator presents a number of difficulties that must be overcome for the system to be secure and stable.
Mehr Ali Qasimi, Asmatullah Nashir
doaj   +1 more source

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