Results 31 to 40 of about 127,505,457 (284)

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Logical Non-Apriorism and the 'Law' of Non-Contradiction

open access: yes, 2004
A common response to those who question the Law of Non-Contradiction (LNC) is that it is impossible to debate such a fundamental law of logic. The reasons for this response vary, but what seems to underlie them is the thought that there is a minimal set ...
Mark Colyvan   +5 more
core   +1 more source

Contradiction [PDF]

open access: yes, 2022
In the second year of the COVID-19 pandemic, the many facets of crisis—the theme of last year's China Story Yearbook—fractured into pictures of contradiction throughout Chinese society and the Chinese sphere of influence.

core   +2 more sources

Crafting an innovative one health-aligned machine learning framework for neglected tropical diseases elimination

open access: yesJournal of Advanced Research
Introduction: Strategic investment in new interventions is crucial for controlling and eliminating NTDs. However, selecting the optimal intervention combination is challenging, especially with limited resources and urgent disease transmission.
Ziyu Zhao   +8 more
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Reasoning By Contradiction in Dynamic Geometry [PDF]

open access: yes, 2013
This paper addresses contributions that dynamic geometry systems (DGSs) may give in reasoning by contradiction in geometry. We present analyses of three excerpts of students’ work and use the notion of pseudo object, elaborated from previous research, to
Mariotti Maria Alessandra   +13 more
core   +1 more source

A Virtual Synchronous Generator Control Strategy Based on Transient Damping Compensation and Virtual Inertia Adaptation

open access: yesApplied Sciences
To mitigate the challenges posed by transient oscillations and steady-state deviations in the traditional virtual synchronous generator (TVSG) that is subjected to active power and grid frequency disturbances, a VSG control strategy based on Transient ...
Yan Xia   +6 more
doaj   +1 more source

Why do violations of FCTC Article 5.3 occur?: The case of tobacco industry incentives in Turkey

open access: yesTobacco Induced Diseases, 2018
Background Aiming at eliminating tobacco industry interference, Article 5.3 forms the backbone of Framework Convention on Tobacco Control (FCTC). By way of analysis of investment and export incentives granted to tobacco industry in Turkey, this research ...
Efza Evrengil
doaj   +1 more source

Do Overconfident CEOs Pay More to Shareholders? Evidence from the US Market

open access: yesКорпоративные финансы, 2020
This paper aims to discover evidence on the possible impact of CEO overconfidence on payout policy, and the role of corporate boards in offsetting the possible negative effects of this overconfidence.
Artem Anilov
doaj   +1 more source

A Comparative study linguistic and literary paradox in the poems of ‛Abd al-wahhāb al-Bayātī and Mohammad Reza šafi’i Kadkani [PDF]

open access: yesادبیات تطبیقی, 2020
A Comparative Study of Linguistic and Literary Paradoxes in the Poems of Abd al-Wahhab Al-Bayati and Mohammad-Reza Shafiei Kadkani*   Hediyeh Ghasemifard 1 Dr.Naser Zare 2                                                                                    
Hediyeh Ghasemifard, Naser Zare
doaj   +1 more source

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