Results 121 to 130 of about 811,407 (258)

ANCA testing strategies: A single centre experience over the past decade in a large teaching hospital in the Netherlands. [PDF]

PLoS One
Wester Trejo MAC, Kuijper TM, Waverijn GJ, Bajema IM, van den Dorpel RMA, Kok MR, Verberk-Jonkers IJAM, Zirkzee EJM, Kos S, Berden AE.   +9 more
europepmc   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

Effect of decay on detection of chronic wasting disease (CWD) in lymph nodes using enzyme-linked immunosorbent assay (ELISA). [PDF]

Prion
Mori J, Barr D, Johnson B, Rivera N, Schlichting P, Skinner D, Novakofski J, Mateus-Pinilla N.   +7 more
europepmc   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

RECENSIONE: Lorenzo PERILLI, Domenico FIORMONTE (a cura di), La macchina nel tempo. Studi di informatica umanistica in onore di Tito Orlandi, Firenze, Le Lettere, 2011, 336 pp.

Diacronie. Studi di Storia Contemporanea, 2013
Laureato in storia a Milano, è dottore di ricerca e cultore della materia in storia contemporanea presso l’Università degli Studi di Trieste. Si occupa di storia del confine orientale d’Italia, associazionismo patriottico, massoneria, irredentismo e nazionalismo tra Risorgimento e Grande guerra. Oltre a numerosi saggi e voci in riviste specializzate, volumi collettanei e repertori biografici, ha pubblicato le monografie Massoneria e irredentismo (Trieste, Irsml, 2015), Da Costantinopoli a Trieste (Milano, Biblion, 2015), Storia del Sanatorio Triestino (Milano, Biblion, 2017) e co-curato Irredentismi (Milano, Unicopli, 2017)
doaj  

Tools per il Virtual Heritage

Storicamente, 2013
Elisa Bassani, Matteo Sgherri
doaj   +1 more source

Epidemiological investigation of Shuni virus infections in hospitals in two provinces of South Africa (2019-2021) using molecular and serological surveillance. [PDF]

PLoS Negl Trop Dis
Rakaki ME, Mendes A, Schreur PW, Groschup MH, Keller M, Du Plessis NM, De Villier M, Avenant T, Venter M.   +8 more
europepmc   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Development of a multi-species luciferase-based double-antigen ELISA for the detection of antibodies against influenza A virus H5 clade 2.3.4.4b. [PDF]

J Clin Microbiol
Aebischer A, Günther A, Piesche R, Wernike K, Murr M, Harder T, Hoffmann D, Grund C, Bellido Martín B, Fouchier R, Daniel K, Ullrich L, Sprute R, Kreer C, Klein F, Roller M, Reese L, Wassermann J, Schares G, Kuryshko M, Abdelwhab EM, Beer M.   +21 more
europepmc   +1 more source

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

Advanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu, Ruo‐xin Wang, Feng He, Qian Liu, Fu‐yin Li, Min Hui, Yu‐qian Shi, Yu Jiang, Qing‐hua Li, Jun‐wen Jing, Shi‐bin Yu, Li‐tian Ma, Qian‐nan Niu, Mian Zhang   +13 more
wiley   +1 more source