Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Serological Cross-Reaction between Six Thiadiazine by Indirect ELISA Test and Their Antimicrobial Activity. [PDF]
Methods Protoc, 2023 Ortiz M +8 more
europepmc +1 more source
, 2013 The purpose of this research was to evaluate herd and cow-level Mycobacterium avium subspecies paratuberculosis (MAP) diagnostic tests within non-infected and low to moderate within-herd prevalence MAP-infected herds. Specific objectives were to estimate
core
Testing the relationship between gut permeability, elevation of systemic lipopolysaccharides and chronic disease : A thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Massey University, Manawatu, New Zealand [PDF]
, 2016 The aim of my thesis was to test whether an increase in the permeability of the gut is accompanied by an increase in the level of systemic lipopolysaccharides (LPS), also referred to as endotoxin.
Gnauck, Anne
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman +9 more
wiley +1 more source
Ahi Evran Medical JournalPurpose: Hepatitis B virus (HBV) infection is a global public health problem with significant morbidity and mortality rates and the detection of HBsAg is a very important test for diagnosis.
Melek Bilgin +3 more
doaj +1 more source
An ELISA Test Able to Predict the Development of Oral Cancer: The Significance of the Interplay between Steroid Receptors and the EGF Receptor for Early Diagnosis. [PDF]
Diagnostics (Basel), 2023 Boccellino M, De Rosa A, Di Domenico M.
europepmc +1 more source
Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan +3 more
wiley +1 more source
Is Immuno-PCR Better than ELISA Test for Detection of Toxoplasma gondii IgG Antibody? [PDF]
Acta Parasitol, 2022 Mardani-Kataki M +4 more
europepmc +1 more source