Results 61 to 70 of about 990,809 (357)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

ELISA Cut-off Point for the Diagnosis of Human Brucellosis; a Comparison with Serum Agglutination Test [PDF]

Iranian Journal of Medical Sciences, 2012
Background: Brucellosis is a world-wide disease, which has a diverse clinical manifestation, and its diagnosis has to be proven by laboratory data. Serum agglutination test (SAT) is the most-widely used test for diagnosing brucellosis.
Anahita Sanaei Dashti, Abdollah Karimi, Vadood Javadi, Farideh Shiva, Fatemeh Fallah, Mohammad Reza Alaei, Goli Angoti, Zahra Pournasiri   +7 more
doaj  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

ELISA test for tuberculosis.

Indian journal of medical sciences, 1994
The Elisa test for diagnosis of tuberculosis using highly purified A 60 antigen extracted from mycobacteria was developed by Anda Biologicals, France, during the late 1980s. It is claimed to have about 95% sensitivity and specificity. Both IgG and IgM antibodies can be separately tested.
V G, Daftary, D D, Banker, G V, Daftary
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The age and residence impact on IgE serum level in patients with allergic asthma

Medical Journal of Babylon
Background: Immunoglobulin E (IgE) has a role in mediating allergic reactions and their powerful effector functions, but numerous factors influence its value.
Raghdah Maytham Hameed, Huda Hadi Al-Hasnawy, Haidar Abdul Amir Najim Abood   +2 more
doaj   +1 more source

Potency of Cell Wall Protein of Pasteurella multocida as Hemorrhagic Septicemia Vaccine on Swamp Buffaloes

Journal of Wetlands Environmental Management, 2020
Vaccine candidate tests were carried out in the Laboratory of Microbiology, Faculty of Agriculture ULM; and the Laboratory of Molecular Genetics, Faculty of Science and Technology Airlangga University.
Herliani Herliani, Abrani Sulaiman, M Ilmi Hidayat   +2 more
doaj   +1 more source

The place and role of serologic methods in detecting Helicobacter pylori infection [PDF]

, 2006
The aim of the study was to determine the place and role of serologic methods in detecting Helicobacter pylori (H. pylori) infection, on the basis of estimated enzyme-linked immunosorbent assay (ELISA) and complement fixation test (CFT) sensitivity and ...
Dominis, Mara, Kalenić, Smilja, Katičić, Miroslava, Marušić, Marinko, Presečki, Vladimir   +4 more
core  

The LISA pathfinder mission [PDF]

, 2015
ISA Pathfinder (LPF), the second of the European Space Agency's Small Missions for Advanced Research in Technology (SMART), is a dedicated technology validation mission for future spaceborne gravitational wave detectors, such as the proposed eLISA ...
Armano, M, Audley, H, Auger, G, Baird, J, Binetruy, P, Born, M, Bortoluzzi, D, Brandt, N, Bursi, A, Caleno, M, Cavalleri, A, Cesarini, A, Cruise, M, Danzmann, K, Diepholz, I, Dolesi, R, Dunbar, N, Ferraioli, L, Ferroni, V, Fitzsimons, E, Freschi, M, Gallegos, J, Gerndt, R, Gesa, L I, Giardini, D, Gibert, F, Giusteri, R, Grimani, C, Harrison, I, Heinzel, G, Hewitson, M, Hollington, D, Hueller, M, Huesler, J, Inchauspé, H, Jennrich, O, Jetzer, P, Johlander, B, Karnesis, N, Kaune, B, Killow, C., Korsakova, N, Lloro, I, Maarschalkerweerd, R, Madden, S, Mance, D, Marirrodriga, C García, Martin-Porqueras, F, Martín, V, Mateos, I, McNamara, P, Mendes, J, Mendes, L, Moroni, A, Nofrarias, M, Paczkowski, S, Perez, J A Romera, Perreur-Lloyd, M., Petiteau, A, Pivato, P, Plagnol, E, Prat, P, Ragnit, U, Ramos-Castro, J, Reiche, J, Robertson, D., Rozemeijer, H, Russano, G, Sarra, P, Schleicher, A, Slutsky, J, Sopuerta, C F, Sumner, T, Texier, D, Thorpe, J, Trenkel, C, Tu, H B, Vetrugno, D, Vitale, S, Wanner, G, Ward, H., Waschke, S, Wass, P, Wealthy, D, Weber, W, Wen, S, Wittchen, A, Zanoni, C, Ziegler, T, Zweifel, P   +89 more
core   +3 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source