Results 81 to 90 of about 990,809 (357)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Combined use of two rapid test in Legionella pneumophila infections

open access: yesMicrobiologia Medica, 2009
Legionella pneumophila serogroup 1 (LPSg1) is the prevalent cause of legionellosis in many geographical areas of the world. LPSg1 infection may presents a severe pulmonary disease whose clinical picture is undistinguishable from that of other ...
Gino Ciarrocchi   +4 more
doaj   +1 more source

Evaluation of ELISA and Brucellacapt tests for diagnosis of human Brucellosis [PDF]

open access: yes
Background and Objectives: Brucellosis is one of the most common zoonotic diseases in Iran and human brucellosis is endemic in all parts of the country. Because of the difficulty in the diagnosis of brucellosis, particularly in endemic areas, the use of ...
پورفرضی, فرهاد   +2 more
core  

Determination of islet cell antibodies using an ELISA system with a preparation of rat insulinoma (RIN A2) cells [PDF]

open access: yes, 1989
An enzyme-linked immunosorbent assay (ELISA) was established for the detection of islet cell antibodies in human sera. The antigen was prepared from rat insulinoma (RIN A2) cells.
Böhm, Bernhard Otto   +5 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Detecţia titrelor de anticorpi postvaccinali împotriva bronşitei infecţioase în condiţii experimentale

open access: yesAgricultural Science, 2012
The article includes the serological investigation of maternal and post vaccination level of specific antibody titers against infectious avian bronchitis, Newcastle disease and bursal disease virus.
OSADCI Natalia   +5 more
doaj  

Enzyme-linked immunosorbent assay for urinary albumin at low concentrations [PDF]

open access: yes, 1987
We describe an enzyme-linked immunosorbent assay (ELISA) for urinary albumin. It requires only commercially available reagents, can detect as little as 16 micrograms of albumin per liter, and analytical recovery ranges from 92 to 116%.
Jesse, U.   +4 more
core  

International Laboratory Comparison of Influenza Microneutralization Assays for A(H1N1) pdm09, A(H3N2), and A(H5N1) Influenza Viruses by CONSISE [PDF]

open access: yes, 2015
The microneutralization assay is commonly used to detect antibodies to influenza virus, and multiple protocols are used worldwide. These protocols differ in the incubation time of the assay as well as in the order of specific steps, and even within ...
Engelhardt, OG   +9 more
core   +1 more source

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