Results 21 to 30 of about 5,978,350 (206)

Muscadine or amla extracts standardized to ellagic acid content ameliorate glucolipotoxicity associated β-cell dysfunction via inhibition of IL-1β and improved insulin secretion

Food Production, Processing and Nutrition, 2020
Glucolipotocixity induces IL-1 β secretion which impairs pancreatic β-cell insulin secretion. Ellagic acid and urolithin A have strong anti-inflammatory effect on cells. Muscadine and amla are very good sources of ellagic acid. The present study examined
Srikanth Earpina, Karen McDonough, Millicent Yeboah-Awudzi, Kristina J. Cook, Sita Aggarwal, Jack N. Losso   +5 more
doaj   +1 more source

Pharmacokinetics study of a supersaturatable self-microemulsifying drug delivery system for ellagic acid by UHPLC-Q-TOF-MS

Acta Pharmaceutica, 2021
To evaluate the bioavailability of ellagic acid loaded super-saturatable self-microemulsifying drug delivery system (S-SMEDDS), its pharmacokinetic properties were studied in rats with an ultra-high performance liquid chromatography-quadrupole time-of ...
Wang Jinglong, Fan Liqun, Zhang Lihua, Zheng Dandan, Wang Yingzi, Sun Xiao, Ji Yonghui   +6 more
doaj   +1 more source

Synthesis of ellagic acid glucoside using glucansucrase from Leuconostoc and characterization of this glucoside as a functional neuroprotective agent

AMB Express, 2021
Ellagic acid glucoside was synthesized via transglucosylation using sucrose and glucansucrase derived from Leuconostoc mesenteroides B-512 FMCM. After such enzymatic synthesis, the product was purified by 50% ethyl acetate fraction and C18 column ...
Hyejin Yu, Hana Jeong, Kwang-Yeol Yang, Jeong-Yong Cho, In Ki Hong, Seung-Hee Nam   +5 more
doaj   +1 more source

Ellagic acid effects on testis, sex hormones, oxidative stress, and apoptosis in the relative sterility rat model following busulfan administration

BMC Complementary Medicine and Therapies, 2022
Background Busulfan is an antineoplastic medication that is broadly utilized for cancer treatment. It affects the testicular function and leads to sterility.
Amirabbas Rostami, S. Vakili, F. Koohpeyma, B. Jahromi, Ziba Afshari Aghajari, Fatemeh Mahmoudikohani, F. Saki, M. Mahmoodi, K. R. Jaberi, A. Movahedpour, Majid J. Khorchani, Saam Noroozi   +11 more
semanticscholar   +1 more source

Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway

Frontiers in Pharmacology, 2021
Idiopathic pulmonary fibrosis is a progressive lung disease with high mortality and limited therapy that is characterized by epithelial cell damage and fibroblast activation.
Xiaohe Li, Xiaohe Li, Kai Huang, Xiaowei Liu, Xiaowei Liu, Hao Ruan, Hao Ruan, Ling Ma, Ling Ma, Jingjing Liang, Jingjing Liang, Yunyao Cui, Yunyao Cui, Yanhua Wang, Shuyang Wu, Hailong Li, Yuli Wei, Zeping Li, Zeping Li, Jingjing Gao, Bo Yang, Xiaoping Li, Guang Yang, Honggang Zhou, Honggang Zhou, Cheng Yang, Cheng Yang   +26 more
doaj   +1 more source

Evaluation of ellagic acid and gallic acid as efflux pump inhibitors in strains of Staphylococcus aureus

Biology Open, 2022
The Gram-positive bacterium Staphylococcus aureus is responsible for a number of infections and has been described to exhibit resistance to antibacterial drugs through different resistance mechanisms.
N. Macêdo, Cristina Rodrigues Dos Santos Barbosa, Antonio Henrique Bezerra, Zildene de Sousa Silveira, Larissa da Silva, H. Coutinho, Saeid Dashti, Bonglee Kim, F. A. D. da Cunha, M. V. da Silva   +9 more
semanticscholar   +1 more source

Nano Ellagic Acid Counteracts Cisplatin-Induced Upregulation in OAT1 and OAT3: A Possible Nephroprotection Mechanism

Molecules, 2020
Cisplatin is an anticancer drug commonly used for solid tumors. However, it causes nephrotoxicity. OAT1 and OAT3 are organic anion transporters known to contribute to the uptake of cisplatin into renal tubular cells.
Thikryat Neamatallah, Nagla El-Shitany, Aymn Abbas, Basma G. Eid, Steve Harakeh, Soad Ali, Shaker Mousa   +6 more
doaj   +1 more source

Preparation of β-CD-Ellagic Acid Microspheres and Their Effects on HepG2 Cell Proliferation

Molecules, 2017
Objective: In this study, β-cyclodextrin (β-CD) was chosen as the coating for ellagic acid to prepare ellagic acid microspheres, and the effect of microspheres on the growth of HepG2 cells was observed.
Hongkai Wang, Yingxia Zhang, Zhongjing Tian, Jing Ma, Meiling Kang, Chengshi Ding, Dongfeng Ming   +6 more
doaj   +1 more source

Anti-Inflammatory Effects of Ellagic Acid on Keratinocytes via MAPK and STAT Pathways

International Journal of Molecular Sciences, 2021
Atopic dermatitis (AD) is a chronic inflammatory skin disease that is characterized by an impaired skin barrier and intense itchiness, which decreases the individual’s quality of life. No fully effective therapeutic agents have prevailed for AD due to an
Tae-Young Gil, C. Hong, Hyo-Jin An
semanticscholar   +1 more source

Ellagic acid inhibits melanoma growth in vitro

Dermatology Reports, 2011
Ellagic is a polyphenolic compound with anti-fibrotic and antioxidant properties as well as exhibits antitumor properties against various cancer cells in vitro. There are few studies, however, which examine the effects of ellagic acid on melanoma.
James Daniel Jensen, Jeffrey H. Dunn, Yuchun Luo, Weimin Liu, Mayumi Fujita, Robert P. Dellavalle   +5 more
doaj   +1 more source