Results 81 to 90 of about 2,686,229 (206)

In Vivo Metabolite Profiling of a Purified Ellagitannin Isolated from Polygonum capitatum in Rats

Molecules, 2016
Ellagitannin is a common compound in food and herbs, but there are few detailed studies on the metabolism of purified ellagitannins. FR429 is a purified ellagitannin with antitumor potential, which is from Polygonum capitatum Buch.-Ham.ex D. Don.
Jing-Yi Ma, Xuelin Zhou, Jie Fu, Chi-Yu He, Ru Feng, Min Huang, Jia-Wen Shou, Zhen-Xiong Zhao, Xiao-Yang Li, Luye Zhang, Yang-Chao Chen, Yan Wang   +11 more
doaj   +1 more source

Effect of myrtle aromatization on chemical profile, sensory perception, and bioactivity of white wine vinegar

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background Vinegar is a popular sour condiment rich in nutrients and bioactive components. Individual sour responsiveness greatly affects vinegar acceptance and diet consumption. In this study, the effect of aromatization with myrtle (Myrtus communis), a health‐beneficial Mediterranean aromatic plant, on the chemical composition, sensory ...
Antonella Rosa, Franca Piras, Flaminia Cesare Marincola, Valeria Sogos, Carla Masala   +4 more
wiley   +1 more source

Effects of DX-9065a, an Inhibitor of Factor Xa, on Ellagic Acid-Induced Plantar Skin Thrombosis Assessed in Tetrodotoxin- and Nω-Nitro-LArginine-Treated Rats

Journal of Pharmacological Sciences, 2003
Effects of DX-9065a ((+)-2S-2-[4-[[(3S)-1-acetimidoyl-3-pyrrolidinyl]oxy]phenyl]-3-[7-amidino-2-naphthyl]propanoic acid hydrochloride pentahydrate), a dibasic propanoic acid and an inhibitor of factor Xa, were compared with those of argatroban, a low ...
Daisuke Chino, Yukiyoshi Fujita, Kunio Ishii, Koichi Nakayama   +3 more
doaj   +1 more source

Therapeutic Potential of Ellagic Acid in Liver Diseases

Molecules
Ellagic acid (EA) is a natural polyphenol found in various fruits, nuts, and mushrooms. It exhibits a variety of biological activities, including potent antioxidant, anti-inflammatory, anti-obesity, and neuroprotective properties. EA exerts hepatoprotective effects through multiple mechanisms, including (1) scavenging reactive oxygen species (ROS) and ...
Karolina Wojtunik-Kulesza, Przemysław Niziński, Anna Krajewska, Tomasz Oniszczuk, Maciej Combrzyński, Anna Oniszczuk   +5 more
openaire   +3 more sources

Ellagic acid attenuates liver toxicity induced by valproic acid in rats

, 2020
Valproic acid is a commonly used drug for many psychiatric disorders, particularly for epilepsy. However, it has been reported that its use is associated with possible side effects including hepatotoxicity.The present study investigated the ...
Amany M. Gad, Naglaa Assaf, Wesam H. Elesawy, Mohammed Elyamany, Noha F. Abdelkader, Hala M. Fawzy   +5 more
core   +1 more source

Investigation Of Ellagic Acid In Human Colon Cancer Cells

, 2023
Cancer is seen as one of the most important and deadly diseases of our time. Colon cancer, which is one of the cancer types and ranks second in cancer-related deaths, is the second most common cancer type in men and the fourth most common cancer type in ...
Karabağ, Funda, Çınar, Muhammed Ali
core   +1 more source

Vaccarin Improves Myocardial Ischemia–Reperfusion Injury by Attenuating Oxidative Stress and Ferroptosis Through Reducing NOX4‐Modulated JAK2/STAT3 Pathway Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Vaccarin is a naturally occurring flavonoid glycoside with cardioprotective properties; however, its involvement in myocardial ischemia–reperfusion (MI/R) injury remains poorly defined. We herein investigated whether vaccarin protects cardiomyocytes from MI/R‐induced dysfunction in vivo and in vitro and examined the associated molecular ...
Han Yang, Mi Zhou, Feng‐Cai Zhang
wiley   +1 more source

Functional Assessment of Platelet‐Derived Phospholipid Activity in Pooled Normal Plasmas by Low‐Phospholipid Thrombin Generation Assay and Its Impact on Lupus Anticoagulant Mixing Tests

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Pooled normal plasma (PNP) used for lupus anticoagulant (LA) mixing tests may carry platelet‐derived phospholipid (PL) activity introduced during freezing/lyophilization, potentially attenuating LA‐mediated prolongation of clotting times.
Osamu Kumano, Masato Matsuda, Mino Sakata, Osamu Maruyama   +3 more
wiley   +1 more source

Metabolic convergence on TOR signaling in the chestnut blight fungus and its regulation by host plant signals

New Phytologist, EarlyView.
Proposed model of metabolic convergence on the target of rapamycin (TOR) pathway in Cryphonectria parasitica. Twelve core genes involved in diverse metabolic pathways act as upstream regulators or downstream effectors of TOR kinase. Dysregulation of these genes mimics an inhibited TOR state, leading to restricted hyphal growth and enhanced trehalose ...
Yo‐Han Ko, Jeesun Chun, Geonmin Kim, Jiwon Yu, Dae‐Hyuk Kim   +4 more
wiley   +1 more source

Assessing the Beneficial Effects of Ellagic Acid in Mitigating Lead Induced Toxicity in Haematopoietic System

Journal of Pharmaceutical Research
Background: Lead exposure causes oxidative stress, leading to hematological abnormalities and immunotoxicity. Ellagic acid (EA) has shown protective effects against lead-induced toxicity in various organs.
Ananya Bhattacharjee, H Venkatrao Kulkarni, V Prasanna Habbu, Manodeep Chakraborty, Nihar Ranjan Bhuyan   +4 more
doaj   +1 more source