Integrated Transcriptomics and Experimental Validation Reveal That Ellagic Acid Alleviates Fuchs Endothelial Corneal Dystrophy via PLAU/NF-κB Signaling. [PDF]
Invest Ophthalmol Vis SciZhou T +6 more
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Ellagic acid mediates cardioprotection against adrenaline-induced toxicity via PI3K/AKT and Keap1-NRF2 axes. [PDF]
Sci RepAldayel TS +7 more
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Ellagic Acid and Its Nanoparticles Mitigate Atherosclerosis by Elevating Low-Density Lipoprotein Receptor Levels Through Targeting of the Epidermal Growth Factor Receptor. [PDF]
FASEB BioadvLi GT +6 more
europepmc +1 more source
Cell type-dependent effects of ellagic acid on cellular metabolism
Biomedicine and Pharmacotherapy, 2018 Ellagic acid is a botanical polyphenol which has been shown to have numerous effects on cellular function. Ellagic acid can induce apoptosis and inhibit the proliferation of various cancer cell types in vitro and in vivo.
Darren F. Boehning
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The metabolism of ellagic acid in the rat
Xenobiotica, 19801. Following oral administration of ellagic acid to the rat, 10% of the dose was excreted as 3,8-dihydroxy-6H-dibenzo[b,d]pyran-6-one in urine and faeces. A second metabolite was detected in urine and faeces but not identified. Both metabolites were of microfloral origin, as their formation was not observed in germ-free rats but was demonstrated when ...
B, Doyle, L A, Griffiths
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Ellagitannins, ellagic acid and vascular health
Molecular Aspects of Medicine, 2010Hydrolysable tannins are phenolic phytochemicals that show high antioxidant and free-radical scavenging activities. For this reason their potential effects preventing oxidative related diseases, such as cardiovascular diseases, have been largely studied.
Mar, Larrosa +3 more
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Spectrofluorimetric determination of ellagic acid in brandy
Food Chemistry, 2012Two spectrofluorimetric methods have been developed for the rapid determination of ellagic acid. The first method is based on the complex formation between ellagic acid and borax in methanol solution. The fluorescence of the complex is monitored at an emission wavelength of 456nm with excitation at 383nm.
Jana, Sádecká, Jana, Tóthová
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Neuroprotective Potential of Ellagic Acid: A Critical Review
Advances in Nutrition, 2021Ellagic acid (EA) is a dietary polyphenol present in various fruits, vegetables, herbs, and nuts. It exists either independently or as part of complex structures, such as ellagitannins, which release EA and several other metabolites including urolithins following absorption.
Ashutosh Gupta +5 more
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Reaction between Ellagic Acid and an Ultimate Carcinogen
Journal of Chemical Information and Modeling, 2005The reaction coordinate between a typical ultimate carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide (BPDE) and ellagic acid, a proven chemopreventive agent active against cancers caused by polycyclic aromatic hydrocarbons (PAHs), was examined by density functional theory (DFT) and semiempirical MO calculations, and activation energy was calculated.
Philippe Huetz +2 more
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Terahertz spectrum of ellagic acid
2009 34th International Conference on Infrared, Millimeter, and Terahertz Waves, 2009The absorption and refractive index of ellagic acid in the range of 0.2–2.4 THz have been measured by THz-TDS. It is found that the ellagic acid has the fingerprint absorption in this frequency region. The vibration absorption spectrum of the single molecule of ellagic acid between 0.2 and 2.4 THz is simulated based on the Density Functional Theory ...
Meng Wu, Guozhong Zhao, Cunlin Zhang
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