Results 21 to 30 of about 2,533,625 (243)

Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway

Frontiers in Pharmacology, 2021
Idiopathic pulmonary fibrosis is a progressive lung disease with high mortality and limited therapy that is characterized by epithelial cell damage and fibroblast activation.
Xiaohe Li, Xiaohe Li, Kai Huang, Xiaowei Liu, Xiaowei Liu, Hao Ruan, Hao Ruan, Ling Ma, Ling Ma, Jingjing Liang, Jingjing Liang, Yunyao Cui, Yunyao Cui, Yanhua Wang, Shuyang Wu, Hailong Li, Yuli Wei, Zeping Li, Zeping Li, Jingjing Gao, Bo Yang, Xiaoping Li, Guang Yang, Honggang Zhou, Honggang Zhou, Cheng Yang, Cheng Yang   +26 more
doaj   +1 more source

Nano Ellagic Acid Counteracts Cisplatin-Induced Upregulation in OAT1 and OAT3: A Possible Nephroprotection Mechanism

Molecules, 2020
Cisplatin is an anticancer drug commonly used for solid tumors. However, it causes nephrotoxicity. OAT1 and OAT3 are organic anion transporters known to contribute to the uptake of cisplatin into renal tubular cells.
Thikryat Neamatallah, Nagla El-Shitany, Aymn Abbas, Basma G. Eid, Steve Harakeh, Soad Ali, Shaker Mousa   +6 more
doaj   +1 more source

Ellagic Acid Enhances RSL3-Induced Ferroptosis by Inhibiting the Nrf2/HO-1 Signaling Pathway in Pancreatic Ductal Adenocarcinoma. [PDF]

FASEB J
Ellagic acid potentiates RSL3‐induced ferroptosis in PANC‐1 by suppressing the Nrf2/HO‐1 antioxidant defense axis via p38 MAPK activation and Keap1 upregulation. In PDAC cells, constitutive Nrf2/HO‐1 signaling establishes a robust antioxidant shield (GPX4, HO‐1) that limits lipid ROS accumulation and confers ferroptosis resistance.
Bai J, Dai Y, Ein Oon C, Hu P, Luo J, Han J, Yang L, Bostani A, Fei Z, Jin Y.   +9 more
europepmc   +2 more sources

Interactions between ellagic acid, solvents and DNA.

, 2021
A) dsDNA model with labels (1 to 40) for the nucleobases. Cytosine is in red, adenine in yellow, thymine in cyan, guanine in green, and phosphorus atoms in orange.
George Malim (11725727), Federico Rossi (1516888), Leonie Jahn (11725724), Emily Kay (11725733), Rebecca Oakey (11725736), Carla Molteni (266197), Logan Kistler (3257139), Rodrigo Feliciano (11725721), Richard Buggs (3285528), Federico Comitani (2821862), Ana Rodriguez Mateos (11725742), Reiner Schulz (18641), Andy Moir (11725739), Alessandro Crnjar (6278483), Laura Southgate (11725730)   +14 more
core   +1 more source

Preparation of β-CD-Ellagic Acid Microspheres and Their Effects on HepG2 Cell Proliferation

Molecules, 2017
Objective: In this study, β-cyclodextrin (β-CD) was chosen as the coating for ellagic acid to prepare ellagic acid microspheres, and the effect of microspheres on the growth of HepG2 cells was observed.
Hongkai Wang, Yingxia Zhang, Zhongjing Tian, Jing Ma, Meiling Kang, Chengshi Ding, Dongfeng Ming   +6 more
doaj   +1 more source

Determination of Ellagic Acid, Punicalagin, and Castalagin from Terminalia ferdinandiana (Kakadu plum) by a Validated UHPLC-PDA-MS/MS Methodology

, 2021
Punicalagin, a bioactive ellagitannin predominantly found in Pomegranate, has a wide range of health benefits including potent antioxidant properties. The metabolism of punicalagin in human body produces urolithins and ellagic acid.
Akter, Saleha, Fletcher, Mary, Hong, Hung, Tinggi, Ujang, Netzel, Michael, Sultanbawa, Yasmina, Osborne, Simone   +6 more
core   +1 more source

Effect of Ellagic Acid on Fermentation Quality and Bacterial Community of Stylo Silage

Fermentation, 2021
This study was conducted to investigate the effect of ellagic acid on the bacterial community and fermentability of stylo silage. Three treatments of stylo silage were used: control (CK) and treated with 1% or 2% ellagic acid (EA1 and EA2) on a fresh ...
Xuan Zou, Dandan Chen, Hongjian Lv, Qing Zhang, Peng Zheng   +4 more
doaj   +1 more source

Research Progress of Extraction, Purification and Bioactivity of Ellagic Acid

Shipin gongye ke-ji, 2022
Plant kingdom is rich in many kinds of natural substances which are beneficial to human health and play a certain auxiliary function to human health. Ellagic acid is a natural polyphenol dilactone found in many fruits and nuts.
Jialuan WANG, Fengyi ZHAO, Chunhong ZHANG, Wenlong WU   +3 more
doaj   +1 more source

Therapeutic Potential of Ellagic Acid in Liver Diseases. [PDF]

Molecules
Ellagic acid (EA) is a natural polyphenol found in various fruits, nuts, and mushrooms. It exhibits a variety of biological activities, including potent antioxidant, anti-inflammatory, anti-obesity, and neuroprotective properties. EA exerts hepatoprotective effects through multiple mechanisms, including (1) scavenging reactive oxygen species (ROS) and ...
Wojtunik-Kulesza K, Niziński P, Krajewska A, Oniszczuk T, Combrzyński M, Oniszczuk A.   +5 more
europepmc   +4 more sources

Antimutagenic effect of ellagic acid and its effect on the immune response in mice

Czech Journal of Food Sciences, 2002
Using the Ames bacterial mutagenicity test and an in vivo micronucleus test, we investigated the antigenotoxic effect of ellagic acid on the genotoxicity of three mutagens: amino-methylimidazo-quinoline (IQ), aflatoxin B1 (AFB1), and N-nitroso-N ...
P. Šmerák, H. Šestáková, Z. Polívková, I. Bárta, B. Turek, J. Bártová, M. Langová, M. Anděl   +7 more
doaj   +1 more source