Results 51 to 60 of about 159,091 (287)

The triaxial ellipsoid dimensions, rotational pole, and bulk density of ESA Rosetta target asteroid (21) Lutetia

, 2010
We seek the best size estimates of the asteroid (21) Lutetia, the direction of its spin axis, and its bulk density, assuming its shape is well described by a smooth featureless triaxial ellipsoid, and to evaluate the deviations from this assumption ...
A. Conrad, B. Carry, Barucci, Barucci, Belskaya, Birlan, Bowell, C. Dumas, C. R. Chapman, Carry, Carry, Chapman, Chapman, Clark, Conan, Conrad, Consolmagno, DeMeo, Drummond, Drummond, Drummond, Drummond, Fienga, Flynn, Fujiwara, Gaffey, H. A. Weaver, J. C. Christou, J. D. Drummond, Kryszczyńska, Lazzarin, Lazzarin, Lazzarin, Macke, Magri, Magri, McCord, Morrison, Mueller, Mugnier, Nedelcu, P. M. Tamblyn, Perna, Rivkin, Rivkin, Shepard, Tedesco, Torppa, Vernazza, Vernazza, W. J. Merline, Weaver, Zellner   +52 more
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Symphonic map from ellipsoid to ellipsoid

, 2023
In this paper, we proved the existence of Symphonic map from ellipsoid to ellipsoid. We also geive give Hopf construction of Symphonic map from ellipsoid to ellipsoid.
openaire   +2 more sources

On the Minimum Volume Covering Ellipsoid of Ellipsoids [PDF]

SIAM Journal on Optimization, 2006
Let ${\cal S}$ denote the convex hull of $m$ full-dimensional ellipsoids in $\mathbb{R}^n$. Given $\epsilon > 0$ and $\delta > 0$, we study the problems of computing a $(1+ \epsilon)$-approximation to the minimum volume covering ellipsoid of ${\cal S}$ and a $(1 + \delta)n$-rounding of ${\cal S}$.
openaire   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Experimental validation of quantum steering ellipsoids and tests of volume monogamy relations

, 2019
The set of all qubit states that can be steered to by measurements on a correlated qubit is predicted to form an ellipsoid---called the quantum steering ellipsoid---in the Bloch ball.
Cheng, Shuming, Guo, Guang-Can, Hall, Michael J. W., Huang, Yun-Feng, Li, Chuan-Feng, Li, Li, Liang, Qiu-Yue, Liu, Bi-Heng, Pryde, Geoff J., Wiseman, Howard M., Zhang, Chao   +10 more
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Lightweight Implicit Approximation of the Minkowski Sum of an N-Dimensional Ellipsoid and Hyperrectangle

Mathematics
This work considers the Minkowski sum of an N-dimensional ellipsoid and hyperrectangle, a combination that is extremely relevant due to the usage of ellipsoid-adjacent primitives in computer graphics for work such as 3D Gaussian splatting.
Martijn Courteaux, Bert Ramlot, Peter Lambert, Glenn Van Wallendael   +3 more
doaj   +1 more source

Measuring the Water Level Datum Relative to the Ellipsoid During Hydrographic Survey [PDF]

, 2011
Hydrographic surveys are referenced vertically to a local water level “chart” datum. Conducting a survey relative to the ellipsoid dictates a datum transformation take place before the survey is used for current navigational products.
Rice, Glen, Riley, Jack
core   +1 more source