This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang+13 more
wiley +1 more source
Book Review: Linear and quasilinear elliptic equations [PDF]
Neil S. Trudinger
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A Supramolecular Material for Controlling Kiwifruit Bacterial Canker
The matrine‐5‐methylsalicylic acid salt (MOS) is reported for its excellent antibacterial activity against Pseudomonas syringae pv. actinidiae (Psa), with advanced cell membrane penetration ability and strong affinities for potential targets. Furthermore, a nanosupramolecular delivery system MOS@hydroxypropyl‐beta‐cyclodextrin (HPCD) with improved ...
Xile Deng+9 more
wiley +1 more source
A Comparison Theorem for Elliptic Differential Equations [PDF]
Charles A. Swanson
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Nanoscale Curvature Regulates YAP/TAZ Nuclear Localization Through Nuclear Deformation and Rupture
This study uses experiments and biophysical modeling to examine the response and adaptation of cells to nanoscale topography of surfaces. It is shown that cytoskeletal assembly and nuclear localization of transcription regulatory factors such as yes‐associated protein (YAP) and transcriptional coactivator with PDZ‐binding motif (TAZ) can be tuned by ...
Emmet A. Francis+7 more
wiley +1 more source
Structural identifiability of linear-in-parameter parabolic PDEs through auxiliary elliptic operators. [PDF]
Salmaniw Y, Browning AP.
europepmc +1 more source
Designing Tunable DNA Condensates to Control Membrane Budding Transformation in Synthetic Cells
In giant unilamellar vesicles (GUVs), membrane wetting of encapsulated liquid‐liquid phase‐separated DNA condensates can be precisely triggered post‐fabrication using photoactivatable DNA‐lipid linkers. On free‐standing membranes, interactions between DNA condensates and the membrane lead to outward budding, resembling exocytosis.
Nastasja Kaletta+3 more
wiley +1 more source
Optimizing Crop Yield Prediction: An In-Depth Analysis of Outlier Detection Algorithms on Davangere Region. [PDF]
Anu CS+3 more
europepmc +1 more source
Engineered Foxp1high Exosomes Ameliorates Systemic Lupus Erythematosus
This study presents a dual‐engineering strategy combining mesenchymal stem cell aggregation and Foxp1 overexpression to generate Foxp1high aggregation exosomes with enhanced immunomodulatory properties. These engineered exosomes exhibit immune organ targeting and superior efficacy in systemic lupus erythematosus treatment by promoting Treg ...
Luhan Niu+9 more
wiley +1 more source
Nonlinear elliptic functional equations in nonreflexive Banach spaces [PDF]
Felix E. Browder
openalex +1 more source