Implicit elliptic equations via Krasnoselskii–Schaefer type theorems
, 2020 Radu Precup
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Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
Advanced Science, EarlyView.MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
wiley +1 more source
A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates
Advanced Science, EarlyView.Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao +7 more
wiley +1 more source
A Study on the Accuracy of Central Difference and Finite Element Techniques for Solving Elliptic Partial Differential Equations [PDF]
Saritha Sambu
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Finite difference method for boundary value problem for nonlinear elliptic equation with nonlocal conditions [PDF]
, 2019 Mifodijus Sapagovas +3 more
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Surrogate-Based Physics-Informed Neural Networks for Elliptic Partial Differential Equations
, 2023 Peng Zhi +5 more
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Advanced Science, EarlyView.We present the MyoRobot 3.0, an advanced platform that combines high‐resolution imaging with automated mechanical testing to improve the accuracy of single muscle fibre analysis. The system tracks fibre diameter changes during stretch, preventing major stress miscalculations.
Michael Haug +5 more
wiley +1 more source
Application of randomized quadrature formulas to the finite element method for elliptic equations. [PDF]
BIT Numer MathKruse R, Polydorides N, Wu Y.
europepmc +1 more source
Advanced Science, EarlyView.Strong‐yet‐ductile precipitation‐hardening alloys require novel microstructural complexity of precipitates in particularly at cryogenic condition, to constantly impart strain hardening of hard‐and‐brittle precipitates. The present work creates innovative structurally complex precipitates assembled with dispersed nanocores and a chemical‐heterogeneity ...
Shaohua Gao +9 more
wiley +1 more source
An Efficient Quasi-Newton Method with Tensor Product Implementation for Solving Quasi-Linear Elliptic Equations and Systems. [PDF]
J Sci ComputHao W, Lee S, Zhang X.
europepmc +1 more source