Results 231 to 240 of about 5,126,960 (286)

Soft Interactions, Rather Than Crowder Size, Determine Deviations From Arrhenius‐Like Kinetics of Phosphofructokinase‐1

open access: yesAngewandte Chemie, EarlyView.
Our study investigates macromolecular crowding effects in the Arrhenius‐like and non‐Arrhenius temperature regimes of the human platelet isoform of phosphofructokinase‐1 (PFKP). The results reveal how PFKP maintains temperature robustness of catalytic activity in differently crowded environments.
Harshita Rastogi   +7 more
wiley   +1 more source

Exploring complex phenomena in fluid flow and plasma physics via the Schrödinger-type Maccari system. [PDF]

open access: yesSci Rep
Abbas N   +6 more
europepmc   +1 more source

Downsizing Electrophilic MAX‐Derived Helical Zipper Peptides to Covalently Bind and Degrade Oncogenic MYC

open access: yesAngewandte Chemie, EarlyView.
Oncogenic MYC is a transcription factor that is difficult to inhibit. However, precise positioning of an acrylamide electrophile in MAX to covalently bond to the unique Cys438 in MYC, enabled shortening and optimizing of MAX‐derived, helix‐constrained peptides with high‐affinity and selectivity.
Aline Dantas de Araujo   +7 more
wiley   +1 more source

Thermo-elastodynamics of nonlinearly viscous solids. [PDF]

open access: yesCalc Var Partial Differ Equ
Almi S   +3 more
europepmc   +1 more source

Control of Helix Screw‐Sense Preference in Dynamic Foldamers of meso Symmetry Built From Chiral Monomeric Units

open access: yesAngewandte Chemie, EarlyView.
Sequence‐diverse meso and “near‐meso” oligourea foldamers are reported and exhibit stimulus‐responsive helix screw‐sense control governed by terminal‐group desymmetrization and sequence‐encoded helix stability. ABSTRACT Meso oligoureas are dynamic hydrogen‐bonded foldamers capable of reversible helix polarity inversion but have so far been limited to ...
Naveen Gupta   +13 more
wiley   +1 more source

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