Results 111 to 120 of about 537 (162)
Ring D modifications of Ellipticine. Part 2. Chlorination of Ellipticine via its N-oxide.
Tetrahedron, 1994 Boogaard, A.T. +2 more
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Search strategies for Characterizing Metastatic Anogenital Squamous Cell Carcinoma in Immunosuppressed Patients: A Systematic Review [PDF]
Antonson, Molly +4 more
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The chemistry of some dihydropyridines and the synthesis of ellipticine derivatives. [PDF]
, 1979 Driver, Michael
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DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF NOVEL HETEROCYCLIC DERIVATIVES AS MODULATORS OF B-DNA AND G-QUADRUPLEXES DNA FUNCTIONS [PDF]
BARTOLOTTA, Roberta
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Journal of Medicinal Chemistry, 1975
Several acyloxy and alkyl derivatives of ellipticine have been prepared. In addition, a modified synthesis leading to the hitherto unobtainable 8,9-dimethoxy- and 8,9-methylenedioxyellipticines is described. Some of the derivatives described herein exhibit antitumor activity.
R W, Guthrie +5 more
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Several acyloxy and alkyl derivatives of ellipticine have been prepared. In addition, a modified synthesis leading to the hitherto unobtainable 8,9-dimethoxy- and 8,9-methylenedioxyellipticines is described. Some of the derivatives described herein exhibit antitumor activity.
R W, Guthrie +5 more
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Biotransformation of ellipticine into 5-formyl ellipticine by Choisya ternata strains
Plant Cell Reports, 1984Sixteen Choisya ternata strains of same genotypic origin were examined for their capacities to biotransform ellipticine. Four strains were able to convert the drug into 5-formylellipticine with good yields. The reaction occurred only in agar medium and was different from ellipticine bioconversion by microorganisms or mammals.
K, Kouadio +4 more
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Ellipticines as DNA-Targeted Chemotherapeutics
Current Medicinal Chemistry, 2014The anti-tumor therapeutic ellipticine and its derivatives act as potent anticancer agents via a combined mechanism involving cell cycle arrest and induction of apoptosis. Cell death induced by ellipticine has been shown to engage a p53-dependent pathway, cell cycle arrest, interaction with several kinases and induction of the mitochondrial pathway of ...
Marie, Stiborová, Eva, Frei
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Tetrahedron Letters, 1984
Abstract The 6H-pyrido[4,3-b]carbazole system is efficiently synthesized by intramolecular attack of an ester enolate on an unactivated pyridinium salt.
Dwight D. Weller, Douglas W. Ford
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Abstract The 6H-pyrido[4,3-b]carbazole system is efficiently synthesized by intramolecular attack of an ester enolate on an unactivated pyridinium salt.
Dwight D. Weller, Douglas W. Ford
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