Results 31 to 40 of about 9,417,936 (292)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Bioecology of Elm Leaf Beetle (Xanthogaleruca luteola (Col.: Chrysomelidae)) in Kermanshah [PDF]

پژوهش‌های حفاظت گیاهان ایران
IntroductionThe elm trees (Ulmus spp.) hold significant ecological, aesthetic, and economic importance in urban landscapes and natural forests. Renowned for their broad, dense canopies, elm trees contribute substantially to improving air quality ...
Mohammadreza Paydar, Abbas Ali Zamani, Arezoo Jamshidi   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

The Logan Elm Press: Children's Picture-Book Competition

, 1984
Print Pages: 1 broadsidePrint Illustrations: ill. (photoengraving)Printing: LetterpressPaper: Canson Mi TientesTypography: Handset CaslonPhysical Dimensions: 50 x 32.2 cmColophon: Designed by Rowena Pon & printed at The Logan Elm ...

core   +1 more source

Effect Modification of Cigarette Smoking on the Relationship between Post‐traumatic Stress Disorder, Other Mental Health Conditions and Rheumatoid Arthritis Risk: A Large Case‐Control Study in U.S. Veterans

Arthritis Care &Research, Accepted Article.
Objective We examined associations of post‐traumatic stress disorder (PTSD) and other mental health disorders (OMH) with rheumatoid arthritis (RA), accounting for effects of smoking. Methods We conducted a matched case‐control study, identifying incident RA cases and controls using national Veteran Health Administration data (2006‐2019).
Kelsey Coziahr, Harlan Sayles, Tate M. Johnson, Joshua F. Baker, Punyasha Roul, Grant W. Cannon, Gary A. Kunkel, Katherine D. Wysham, Gail S. Kerr, Amir A. Razmjou, Isaac Smith, Jennifer L. Barton, Maria I. Danila, Jonathan S. Richards, Bryant R. England, Ted R. Mikuls   +15 more
wiley   +1 more source

An ELM based predictive control method for HCCI engines [PDF]

Engineering Applications of Artificial Intelligence, 2016
We formulate and develop a control method for homogeneous charge compression ignition (HCCI) engines using model predictive control (MPC) and models learned from operational data. An HCCI engine is a highly efficient but complex combustion system that operates with a high fuel efficiency and reduced emissions compared to the present technology.
Vijay Manikandan Janakiraman, XuanLong Nguyen, Dennis Assanis   +2 more
openaire   +2 more sources

From Food to Power: Hydrogel Thermoelectrics for Ingestible Electronics

Advanced Functional Materials, EarlyView.
We introduce a fully edible thermoelectric–electrochromic platform that harvests heat from food and converts it into a visible color change. N‐type and p‐type hydrogel thermoelectric generators connected in series power anthocyanin‐based electrochromic displays, demonstrating the feasibility of safe, biodegradable, ingestible systems for on‐food ...
Antonia Georgopoulou, Bokeon Kwak, Dario Floreano, Esther Amstad   +3 more
wiley   +1 more source

Mid-Ohio Elegies

, 1985
Print Edition: 165 copies.Print Pages: 32 p.Print Illustrations: 5 ill. (collotype) + with woodcut on coverPrinting: LetterpressBinding: Double-section saddle-stitch; Self-wrappedPaper: Mohawk Letterpress; Fabriano Roma CoverTypography: Monotype ...
Grigsby, Gordon
core   +1 more source

A new type of resonant magnetic perturbation for controlling edge localized modes

Nuclear Fusion
A new type of resonant magnetic perturbation (RMP), generated by helical coils, is proposed for controlling the edge localized mode (ELM) in H-mode tokamak plasmas. The helical coil optimization utilizes the MARS-F code (Liu et al 2000 Phys.
Xu Yang, Yueqiang Liu, Xuan Sun, Wei Xu, Li Li, Yuling He, Guoliang Xia, Hanqing Hu, Lina Zhou   +8 more
doaj   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source